Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"TRBP"”.
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Regulation of Pkr Activation by Pact and Trbp In Response to Stress Signals
… region (TAR) RNA-binding protein (TRBP). The purpose of this study is to understand the mechanism of PACT-mediated PKR activation and to define its functional importance in stress-induced apoptosis. In particular, we have investigated the role of stress-induced phosphorylation of …
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Enhancement of Dicer as a personalized anticancer strategy
… pathway like Dicer, TAR RNA-binding protein (TRBP) and Drosha. Herein, the enhancement of miRNA processing as a therapeutic strategy is explored. Developing small molecule or peptide based therapeutics that mimic TRBP, an endogenous activator of Dicer, to enhance miRNA processing in cancers …
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Single molecule pull down of double strand RNA binding proteins
… Here we examined four human dsRBPs, ADAD2, TRBP, Staufen 1 and ADAR1 `which have various numbers of RNA binding domains expressed in mammalian cells. We applied single molecule pull-down (SiMPull) assay to investigate the intensity of various dsRNA-dsRBP interactions. Our results demonstrate …