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Showing 1 to 3 of 3 for “"TRAF proteins"”.

  1. Determinants of protein-peptide interaction specificity in the Bcl-2 and TRAF families

    … families discussed in this work, Bcl-2 and TRAF proteins, have roles in cellular processes including apoptosis, inflammation, and immunity. Aberrant function of these proteins has been linked to a variety of diseases. There is great interest in understanding the mechanistic basis of …

    mit Repository record for Determinants of protein-peptide interaction specificity in the Bcl-2 and TRAF families (opens in a new tab)

  2. Mechanisms of TRAF Signaling

    … by tumor necrosis factor (TNF) superfamily proteins. Ligands of the TNF family engage TNF receptor (TNFR) family proteins, leading to a wide variety of cellular effects, these interactions are implicated in inflammation, immune regulation, bone homeostasis, and development. TNFR proteins

    rockefeller Repository record for Mechanisms of TRAF Signaling (opens in a new tab)

  3. Investigating the function of TRAF1 in NF-κB activation

    … necrosis factor receptor-associated factor (TRAF) proteins play an important role in mediating the activation of NF-κB. Dysregulation of NF-κB may be one of the potential causes of chronic inflammatory diseases. One member of the TRAF family, TRAF1, has been shown to increase the risk of …

    york Repository record for Investigating the function of TRAF1 in NF-κB activation (opens in a new tab)