Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"TP508"”.
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RADIOSENSITIZING EFFECTS OF THROMBIN PEPTIDE TP508 ON MEDULLOBLASTOMA CANCER STEM CELLS
… our laboratory showed that thrombin peptide TP508, a novel 23-amino acid investigational drug, protects normal neural stem cells from ionizing radiation damage. To determine whether the peptide would also protect brain CSCs from radiation damage, I examined the effects of TP508 on the …
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PEGylated Tissue Repair Peptide TP508 Derivatives as Second Generation Drugs for Radiomitigation and Other Systemic Applications
TP508 is a therapeutic peptide that represents a specific receptor-binding domain of human thrombin with many potential clinical applications. However, it shares several weaknesses common to peptides when administered systemically, such as a short circulating half-life and rapid proteolytic …
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Insights into the mechanisms of wound repair and the role of TP508 in tissue regeneration
… adherens junctions and the tissue repair peptide TP508 as a potential modulator of inflammatory-induced endothelial activation. Second, these experiments aimed to determine how TP508 promoted dermal wound healing using two models of impaired dermal healing. To gain insights into the mediators of …