Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"TNF-a signaling"”.
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Regulation of Tumor Necrosis Factor-alpha Signaling in Rheumatoid Arthritis Synovial Fibroblasts by Green Tea Polyphenol Epigallocatechin-3-gallate
… interleukin (IL)-1β and tumor necrosis factor (TNF)-α, stimulate synovial fibroblast proliferation leading to joint damage and destruction. Epigallocatechin-3-gallate (EGCG) is a polyphenol found in green tea that has been shown to have an anti-inflammatory effect in RA. Previous studies suggest …
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Targeting PI3K Isoforms to Improve Effectiveness of T Cells Mediated Immunotherapy
… profiling revealed the upregulation of TNF-a signaling in PTEN-present tumors and the upregulation of genes associated with cell cycle, apoptosis, and immune response in PTEN-absent tumors after PI3Ka inhibition. In conclusion, our results provide a strong rationale for the clinical …
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Direct Regulation of Apoptosis By Linear Ubiqutin Chain Assembly Complex (Lubac) and Feedback Regulation of Lubac Function By Caspases
<p>Tumor Necrosis Factor-alpha (TNF-α) is a cytokine that plays a role in various cellular processes such as proliferation, differentiation (mainly through NF-κB signaling) and death (via apoptosis signaling). Recently, linear ubiquitination by LUBAC (linear ubiquitin chain assembly complex) was …