Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"TMT proteomics"”.
-
Comparative Plasma Proteomics in Muscle Atrophy Induced by Cancer Cachexia and Hindlimb Unloading
… Plasma was analyzed by tandem mass tag (TMT) proteomics. Results: Raw plantaris weight was significantly lower in LLC (22.7%) and HU (18.6%) groups compared to control (p<0.05), but not different from each other (p>0.05). Equivalent tibia sizes across groups suggest no significant …
-
An omics study into the molecular impact of autosomal dominant APP and MAPT mutations on the cerebral cortex
… I describe the generation of transcriptomics and proteomics datasets with the goal of uncovering transcriptional and translational pathways driving AD linked to APP and MAPT mutations. The first half of this thesis focuses on the differentiation of patient-derived iPSCs carrying MAPT E10+16 and …
-
Identification and Characterisation of Human Cytomegalovirus-Mediated Degradation of Helicase-Like Transcription Factor
Viruses are known to degrade host factors that are important in innate antiviral immunity in order to infect successfully. To systematically identify host proteins targeted for early degradation by human cytomegalovirus (HCMV), the lab developed orthogonal screens using high resolution multiplexed …