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Showing 1 to 7 of 7 for “"TMPRSS2:ERG"”.

  1. Tmprss2-Erg Regulation Of Androgen Biosynthetic Enzyme Expression, Dht Synthesis, And Androgen Receptor Activation In Prostate Cancer

    … biosynthetic enzyme gene expression in PCa. The TMPRSS2-ERG transcription factor has been shown to be present in primary PCa tumors as well as CRPC tumors. The hypothesis was investigated that TMPRSS2-ERG fusions regulate androgen biosynthetic enzyme (ABE) gene expression and the production of …

    wayne-thes Repository record for Tmprss2-Erg Regulation Of Androgen Biosynthetic Enzyme Expression, Dht Synthesis, And Androgen Receptor Activation In Prostate Cancer (opens in a new tab)

  2. Image analysis of prostate cancer tissue biomarkers

    … studies, we investigated the expression of ERG (as a surrogate marker of TMPRSS2:ERG gene fusion status) and TATI (encoded by SPINK1) proteins in a large TMA of localized prostate cancer patients. We observed a mutually exclusive expression pattern, further supporting the idea of tailored …

    lund Repository record for Image analysis of prostate cancer tissue biomarkers (opens in a new tab)

  3. Diagnostic and Prognostic Biomarkers for Early Prostate Cancer

    … by focusing on DNA methylation, and PTEN and ERG protein markers in a large biomarker study. During this study we overcame several technical challenges associated with a typical biomarker discovery/validation approach such as cohort development and sample collection, and recovery of …

    queens Repository record for Diagnostic and Prognostic Biomarkers for Early Prostate Cancer (opens in a new tab)

  4. Identifying genetic biomarkers for diagnosis of prostate cancer in South African men

    … DLC1, upregulated genes included; CDH1, MKI67, TMPRSS2, ERG, CDKN2A, FASN, and AR but were not statistically significant. At a fold change threshold of 1.5, the following additional genes were downregulated in the PCa group with p values <0.05; DAXX, EGFR, RASSF1, SOX4, and TIMP2, upregulated …

    cape-town Repository record for Identifying genetic biomarkers for diagnosis of prostate cancer in South African men (opens in a new tab)

  5. Proteomic Profiling of Serum Derived Exosomes from Prostate Cancer Patients

    … methylacyl-CoA, and the gene fusion product TMPRSS2-ERG. More recently Zhang, Casiano and colleagues described an increased predominance of autoantibodies to Cyclin-B1 in the sera of PCa patients compared to controls with Benign Prostatic Hyperplasia (BPH). All these efforts are in different …

    loma-linda Repository record for Proteomic Profiling of Serum Derived Exosomes from Prostate Cancer Patients (opens in a new tab)