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Showing 1 to 1 of 1 for “"TMEM2"”.
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Identification of TMEM2 as a SOX4 Transcriptional Target Involved in Breast Cancer Metastasis
… we identify the transmembrane protein 2 (TMEM2) gene as a direct transcriptional target of SOX4. TMEM2 is transcriptionally activated by SOX4 in both breast cancer and lung adenocarcinoma cells and mediates pro-invasive and pro-migratory effects of SOX4. TMEM2, like SOX4, is sufficient to …