Global ETD Search
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Showing 1 to 1 of 1 for “"TMEM175"”.
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The effects of the Parkinson’s disease-associated proteins LRRK2 and TMEM175 on the lysosomal profile of cultured mammalian cells under lysosomal stress conditions
… gene encodes the transmembrane protein 175 (TMEM175), a lysosomal cation channel essential for maintaining lysosomal pH and regulating other aspects of endolysosomal function. The mechanisms by which the mutations in LRRK2 or TMEM175 cause PD have not yet been established, which hinders the …