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Showing 1 to 2 of 2 for “"TMED10"”.

  1. Molecular Mechanisms of SURF4- mediated Protein Secretion

    … is due to a PCSK9 requirement for a co-receptor, TMED10. Using a protein-protein interaction assay and various SEC24 and SURF4 binding mutants, I showed that SURF4 uses C-terminal hydrophobic and acidic amino acids to bind the B-site on SEC24C. Conversely, SEC24A recognises a cytosolic loop on …

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  2. THE ROLE OF P24 PROTEINS IN THE ER TO GOLGI TRANSPORT OF TOLL-LIKE RECEPTORS

    … In addition, CRISPR-Cas9 knock-out of TMED2 and TMED10 in HEK293T cells resulted in poor cell viability implying that some members of the p24 family are important for normal cellular functions. To investigate the oligomeric properties of TMED7, recombinant TMED7 ectodomain was produced in HEK293T …

    cambridge Repository record for THE ROLE OF P24 PROTEINS IN THE ER TO GOLGI TRANSPORT OF TOLL-LIKE RECEPTORS (opens in a new tab)