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Showing 1 to 20 of 26 for “"TMB"”.

  1. Assessing Tumor Mutation Burden and Correlation With Anti-PD-1/L1 Therapy Benefit and Prognosis

    Muquith, MaisharaUT Southwestern Medical Center2024

    … across all cancer types. Tumor mutation burden (TMB) is postulated to be a generic determinant of ICI dependent-tumor rejection. Here, we clarify the association between TMB and survival outcomes among microsatellite-stable cancers in a real-world clinicogenomic cohort including 70,698 patients …

    utswmed Repository record

  2. Machine learning applications for the topology prediction of transmembrane beta-barrel proteins

    Grimaldi, Cédric MaximeLondon Metropolitan University2022

    … of transmembrane alpha-helices. The efforts to TMB (transmembrane beta-barrel) proteins topology prediction have been overshadowed, and the prediction accuracy could be improved with further research. Various methodologies have been developed in the past to predict TMB proteins topology. Methods …

    london-metro Repository record

  3. A DOAS Study on the Oxidation Mechanism of Aromatic Hydrocarbons under Simulated Atmospheric Conditions

    Volkamer, RainerUniversität Heidelberg

    … Toluol, p-Xylol (BTX) und 1,3,5-Trimethylbenzol (TMB)) zu verbessern. Diese Mechanismen gelten als Hauptunsicherheitsfaktoren in Chemie-Modellen zur Erfassung der Photooxidantienbildung aus Stadtluft. Differentielle Optische Absorptions Spektroskopie (DOAS) wurde in einer systematischen …

    heid-diss Repository record

  4. The synthesis of stable nanotags for the detection of biomolecules using surface enhanced Raman scattering

    Sloan-Dennison, SianUniversity of Strathclyde2017

    … such as 3,3',5,5'-tetramethylbenzidine (TMB) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonate) (ABTS) and in the presence of hydrogen peroxide (H2O2). This yields a colorimetric response which can be characterised using ultraviolet-visible (UV-vis) spectroscopy, Resonance Raman …

    strathclyde Repository record

  5. Using the Electronic Medical Record to Ensure Compliance with Opioid Prescription Laws in Texas

    Bender, Christopher McLean2021

    … chronic pain. The state of Texas medical board (TMB) enacted a law change that restricts and regulates the prescribing and dispensing of controlled substances with respect to patients experiencing chronic pain. LOCAL PROBLEM: At the onset of this project, the University of Texas Southwestern …

    utswmed Repository record

  6. Atmospheric Chemistry of Volatile Organic Compounds: Oxidation Products, Mechanisms and Secondary Organic Aerosol Formation

    Hammes, Julia2019

    … biogenic VOC) and 1,3,5- trimethylbenzene (TMB) (an anthropogenic VOC) were studied in the G-FROST and Go:PAM flow reactors to characterize their oxidation and the subsequent SOA-forming processes. Previously unknown compounds including dimer esters, carboxylic acids, nitrates and highly …

    goteborg Repository record

  7. Application of the transformation of 1,2,4-Trimethylbenzene to monitor the chemical vapour deposition of Tetraethoxysilane over ZSM-5

    Röger, Hans PeterDepartment of Chemical Engineering1998

    … transformation of 1,2,4-trimethylbenzene (1,2,4-TMB) was investigated with respect to the reaction network, the role of the micropore space and the response to CVD treatments and Silicalite I coating. A generalised interpretation of the effect of modifications of the external surface activity and …

    cape-town Repository record

  8. Aprimoramento do diagnóstico de Leishmaniose visceral canina por ELISA usando o antígeno NTPDase-2 de Leishmania (Leishmania) infantum chagasi e padronização do diagnóstico por imunocromatografia

    Souza, Anna Cláudia Alves deUniversidade Federal de Viçosa2016

    … diferentes substratos de desenvolvimento de cor (TMB e OPD) para revelação. A influência da conformação do antígeno foi avaliada usando-o em condição nativa ou desnaturada. Na padronização do ELISA, 0,1 µg de antígeno e diluição do soro 1:160 foram as melhores condições. O uso de TMB e OPD não …

    brazil-ufv Repository record

  9. Cloning and characterization of the Pichia Pastoris PMR1 gene

    Grove, Heather Lee2005

    … determined using 3,3',5,5' tetramethylbenzidine (TMB) colorimetric assay and western analysis. β-gal expression and secretion was determined by western analysis. Secretion in P. pastorius Δpmr1 for both heterologous proteins showed no appreciable difference compared to wild type, nor did P. …

    u-pacific Repository record

  10. Mikrowellenplasma-Simulation, Abscheidung und Charakterisierung von polykristallinen, dotierten und undotierten Diamantschichten

    Pleuler, Erik

    … für Bor wird flüssiges Trimethylborat (TMB) verwendet. Mit Hilfe einer Gasmischanlage können die Bor-Konzentrationen über fünf Größenordnungen variiert und unterschiedlich stark dotierte Proben abgeschieden werden. SIMS-Messungen geben Aufschluss über die erzielten Dotierkonzentrationen …

    freiburg-diss Repository record

  11. Plasma Facing Components conditioning techniques and their correlation with plasma performance in the National Spherical Torus eXperiment Upgrade (NSTX-U)

    Bedoya Arroyave, Carlos FelipeUniversity of Illinois at Urbana-Champaign2018

    … boronization with deuterated-Trimethylboron (d-TMB) results in a coating of B4C, with thick- ness greater than 10 nm. The concentrations of the deposits were measured following several boronizations, and in average, the composition was around 33% B, 5%O and 64%C. Good plasma performance was in …

    uiuc Repository record

  12. Aminoxyl Catalyzed Electrochemical Ethanol Detection: Development of a New Breathalyzer Using Molecular Catalysis

    Mayer, Mikayla NoelleUniversity of Missouri--Kansas City2021

    … 1-oxyl benzoate (TMB) was the most efficient derivative. Exposing this modified electrode to simulated breath that contains ethanol, while applying the required potential for oxidation of the aminoxyl radical, generates an electrocatalytic current proportional to …

    umkc Repository record

  13. Nanostructured carbohydrate-derived carbonaceous materials

    Kubo, ShioriUniversität Potsdam

    … pore swelling additive (e.g. trimethylbenzene (TMB)) to this system was found to direct pore size into the mesopore size domain (i.e. Type IV isotherm, SBET = 116 m2g-1, 60 % mesoporosity) generating pore size of ca. 4 nm. It is proposed that in both cases as HTC proceeds to generate a …

    potsdam-diss Repository record

  14. An ecological adjusted random effect model for violent and property crime in Windhoek (2011-2016)

    Amunyela, JonasUniversity of Namibia2020

    … Linear Mixed Model via Template Model Builder (TMB) R-package. The researcher considered the number of reported Property and Violent crime for the study period as a quantitative design. Crime was counted with respect to Month, Season, Year, Location and Density. Through an exploratory study, it …

    namibia Repository record

  15. The response of human spermatozoa to chemoattractants

    Morales Garcia, Auden AndresUniversity of Birmingham2010

    … in low [Ca\(^{2+}\)]o but was unaltered by TMB-8 (an inhibitor of stored Ca\(^{2+}\) store release), thus showing a dependence on Ca\(^{2+}\) influx similar to the [Ca\(^{2+}\)]i signal.

    birmingham Repository record

  16. Investigation and design of SERS active nanoparticle assemblies via biological interactions

    Craig, DerekUniversity of Strathclyde2013

    … Successful detection has been achieved in a TMB ELISA format indicating that the biological integrity of the biomolecules attached to these nanotags remains intact following their functionalisation. Following the success of the linkers devised for nanotags synthesis several novel short chain …

    strathclyde Repository record

  17. Higher order chromatin degradation induced by hydrogen peroxide in glial cells

    Mouzannar, Raymond2019

    … (N,N-diethylamino)-ocyl-3,4,5-trimethoxybenzoate (TMB-8) affected the digestion. Moreover, increasing intracellular calcium with A23187 calcium ionophore did not induce HOCD. These results indicate that HOCD is not directly mediated by calcium, but resting level of calcium is required for the …

    wvu Repository record

  18. Tin Sensitization For Electroless Plating

    Wei, Xingfei2017

    … 3,3',5,5'-tetramethylbenzidine dihydrochloride (TMB-d) was developed for determining low concentrations of tin(II). In Chapter IV the spectrophotometric method developed in Chapter II was developed for quantitative measurement of stannous (tin(II)) concentrations on ceramic substrates. Effects of …

    arkansas Repository record

  19. TREMELIMUMAB AND DURVALUMAB COMBINATION FOR THE NON-OPERATIVE MANAGEMENT OF MICROSATELLITE INSTABILITY HIGH RESECTABLE GASTRIC OR GASTROESOPHAGEAL JUNCTION CANCER: RESULTS OF COHORT 1 OF THE MULTICENTRE, SINGLE-ARM, MULTI-COHORT, PHASE II INFINITY STUDY

    PRISCIANDARO, MICHELEUniversità degli Studi di Milano2022

    … verso la significatività nei diverso valore di TMB basale è stata osservata in quei pazienti che avevano raggiunto la pCR con immunoterapia rispetto a quelli che non avevano raggiunto tale risultato. Per quanto riguarda il profilo di sicurezza, non sono stati segnalati eventi avversi inattesi o …

    milano Repository record

  20. 1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine (Platelet Activating Factor): Interactions with Sheep Platelets

    Beaumont, Duane O.

    … of platelet activation such as prostacyclin, TMB-8 and indomethacin, had similar effects on the magnitude of response by aggregation and SCP assay. Both ATP release and SCP were inhibited in proportion to the concentration of prostacyclin. Neither aggregation nor SCP was affected by …

    loma-linda Repository record

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