Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"TMAs"”.
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Assessing Transportation Management Associations (TMAs) In Rural Maine As An Approach To Increase Transportation Options
<p>Maine has the distinction of being a beautiful state defined by natural forests, crystal-clear lakes, and a landscape unblemished by the usual marks of the densely populated regions of the U.S. The downside to this rural beauty is the remoteness of the sparsely populated communities which …
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Multi-scale computational modeling of particle adhesion dynamics under shear flow
… diseases like thrombotic microangiopathies (TMAs). By modeling interactions between VWF and platelets under physiological shear conditions, a stable web-like scaffold was formed, resulting in a complex network of cross-linked VWF and platelets that may contribute to microvascular obstruction. …
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Accuracy of Heat-Pulse Sensors for Determining Moisture of Capillary Mat Material Used to Support Plant Growth
… WI) Thermal and Moisture Acquisition System (TMAS) sensors were investigated for use in the WONDER space flight experiment. WONDER is studying the effect of multiple wetness level regimes and two different nutrient delivery systems (NDS) on plants grown in the microgravity of space. The …
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Academic procrastination among graduate vs. undergraduate students and differences in the experience of affective and cognitive factors
… Scale, the Taylor Manifest Anxiety Scale (TMAS), and the Center for Epidemiologic Studies Depression Scale (CES-D).</p>
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Estudio clínico-patológico e inmunohistoquímico de los carcinomas cutáneos escamosos de alto riesgo de cabeza y cuello
… con CCE y la construcción de tissue microarrays (TMAs).
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Computational methods for cancer diagnosis and prognosis from FT-IR spectroscopy data
… imaging. We employ tissue microarrays (TMAs) to record IR imaging data and adopt elaborated computational and analytical algorithms and statistical methods to recognize patterns and to construct robust systems. We firstly suggest a statistical framework to examine FT-IR imaging from a …
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Analysis of breast tissue microarray spots
Tissue microarrays (TMAs) are a high-throughput technique that facilitates the survey of very large numbers of tumours, important both in clinical and research applications. However, the assessment of stained TMA sections is laborious and still needs to be carried manually, constituting a …
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Explorative studies to understand if aldehyde dehydrogenase (ALDH) expression in colon cancer can be exploited as a target for therapeutic intervention. Expression profiling of ALDH7A1 in colorectal cancer
… in CRC xenografts and tissue microarrays (TMAs) revealing hypoxia also impacts on ALDH7A1 expression in clinical samples. Both ALDH1B1 and ALDH7A1 were shown to be highly expressed in all patient samples, however, in-depth mechanistic studies are required to fully elucidate the role of …
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Poly(ethylene glycol)-based open-channel blockers for the acetylcholine receptor : mechanistic and structure-function studies at the single-channel level
… conjugates show that short bivalent PEG-TMAs containing four to thirteen ethylene oxide units in the backbone block the open AChR in a length-dependent manner. Both the blocking and unblocking rate constants decrease with increasing backbone length. Replacing the TMA moiety with other …
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FANCD2 in relation to BRCA2 mutated breast cancer
… on 470 BC samples on tissue microarrays (TMAs). It was evaluated whether overexpression of these proteins in the cell nuclei were associated with clinicopathological parameters or BC specific survival emphasizing BRCA2 mutation carriers. Another aim was to look for improved therapy options …
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Genomic Characterization of Recurrent Chromosomal Aberrations in Retinoblastoma
… genes in two pre-constructed tissue microarrays (TMAs) comprising 270 retinoblastoma patient tumours. Results show 1q gain (3-10 copies) in 136/262 (52%), 6p gain in 127/262 (48.7%), MYCN gain in 18/265 (6.8%) and MYCN amplification (>10 copies) in 20/265 (7.5%) patient tumours. MYCN amplification …
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The role of tissue inflammation in Kenyan women with breast cancer
… TIL working group. Tissue Microarrays (TMAs) of tumour were constructed, stained with immunohistochemistry for CD3, CD4, CD8, CD68, CD20 and Fox P3, scanned and analysed on the Leica Aperio platform. Cytokine profiles of ER positive and Triple Negative BC were performed using microarray …
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Time-Modulated Array Testbed Prototype for Multibeam Spectrometry
… experimental studies of time-modulated arrays (TMAs). The design includes in-lab development of antenna elements, systems development of the heterodyne receiver architecture, and development of firmware and software for receiving and analyzing RF signals. The TMA antennas and radios are designed …
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The role of receptor tyrosine kinase signalling in HER-2-positive cells and trastuzumab (Herceptin) resistance in breast cancer
… by immunohistochemistry in tissue microarrays (TMAs) of patient breast tumour samples. Membrane IGF-IR staining correlated inversely with HER-2 expression (p = 0.026). In conclusion, these data suggest that increased signalling through alternative RTKs may play a role in acquired resistance to …
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Immunohistochemical and molecular studies on ovarian cancer progression and prognosis
… Malmö Preventive Project. Tissue microarrays (TMAs) were constructed with primary ovarian tumour samples from all cases, omental deposits from 33 cases and benign-appearing fallopian tubes from 38 cases. In addition, an independent gene expression data set with 285 EOC cases was analyzed, and …
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Differential treatment of test anxiety utilizing group systematic desensitization and relaxation training
… post-test scores on the general anxiety measure (TMAS) for any of the groups. Group I showed a significant loss on the scholastic achievement measure, and the trend for the other groups was toward loss rather than gain. The reasons for this are not clear, but some possibilities are listed in the …
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Immune Infiltrates in Breast Cancer: Clinical Significance from Histopathology to Prognosis
… (BCAC) tissue microarray (TMA) dataset. TMAs are cassettes designed to efficiently organise cylindrical tumour samples (cores) from a large number of patients, and stain their horizontal sections for a variety of targets. BCAC’s TMA dataset is composed of 137,181 core images from 18,088 …
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Immunzellen in primären und metastasierten gastrointestinalen Stromatumoren (GISTs)
… Empfängerparaffinblock (TMA) nebeneinander in 22 TMAs aufgereiht. Die Fotographien von jeweils 3-6 Stanzen erbrachten durch die computergestützte Auswertung mit nachfolgender statistischer Auswertung der Ergebnisse sehr genaue Angaben der prozentualen Anzahl von Immunzellen in den jeweiligen …
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Proteomics characterization of HPV-independent Vulvar Cancer Tumour Progression and Metastasis by Mass Spectrometry
… Two vulvar cancer VSCC tissue microarrays (TMAs) built from 28 patient samples (16 LNM positive and 12 LNM negative) were analyzed using the MALDI-MSI data. Peptide peaks of N-myc downstream regulated 1 (NDRG1) and Annexin 8 (ANXA8) showed higher discriminative powers in the Receiver …
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Image analysis of prostate cancer tissue biomarkers
Prostate cancer is the second most common cancer in men. In order to improve diagnosis and prognosis, new sensitive and specific biomarkers are needed. Tissue biomarkers carry expression and morphological information of the tissue where they are expressed. However their use is still limited by …