Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"TLR6"”.
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Immunomodulation of commercial line and Piau Brazilian Naturalized breed pigs in response to vaccination against Mycoplasma hyopneumoniae and Pasteurella multocida type D
… teve maior expressão de mRNA para TLR2, TLR4, TLR6 e TLR10 e as citocinas IL6 e TNFα depois da vacinação que antes da vacinação, enquanto os animais da raça Piau mostraram maior expressão para TLR6, TLR10, TNFα e TGFβ. Em relação às amostras de BALF, os animais vacinados da raça Piau tiveram …
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Molecular Pathogenesis of MALT lymphoma
… expression of NF-κB target genes, particularly TLR6, CCR2, CD69 and BCL2, while translocation-negative cases were featured by active inflammatory and immune responses, such as IL8, CD86, CD28 and ICOS. Separate analyses of the genes differentially expressed between translocation-positive and …
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Deciphering the relationship among nutrition, host and microbe
… and intestinal epithelial cells. Using TLR1 and TLR6 knockout mice, these studies aim to understand how disruption in host recognition of the microbiota can exacerbate disease. In Chapter 5, aberrant TLR1 signaling led to increased mucosal-adherent microbes and defective mucosal immunity. These …
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Defining the mechanisms of microbial sensing among members of the toll-like receptor 2 sub-family
… by forming heterodimers with either TLR1 or TLR6, respectively. Crystal structure analysis revealed that triacylated bacterial lipoproteins coordinately bind TLR1 and TLR2 resulting in a stable ternary complex that drives intracellular signaling. However, the order of complex formation upon …
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THE ROLE OF IL-¿¿1 RECEPTOR-¿¿ASSOCIATED KINASE 4 IN MICROGLIAL ACTIVATION IN ALZHEIMER’S DISEASE
… CD36, CD47, SRA, ¿¿6¿¿1 integrin, TLR2, TLR4, TLR6, and CD14. The role of individual TLRs in the microglial response to A¿¿ has been controversial. Therefore we elected to inactivate the first kinase activated after TLR ligation, interleukin-¿¿¿1 receptor-¿¿associated kinase 4 (IRAK4), to …
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Evolutionary analysis of Suidae TLR signaling pathway
… of bacterial sensing TLR (TLR1, TLR2 and TLR6) and viral sensing TLR (TLR3, TLR7 and TLR8) were retrieved from resequencing libraries of one animal representing each of the following members of the family Suidae: Sus scrofa from Europe, Sus scrofa from Asia, Potamochoerus larvatus, …
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Understanding functional mechanisms of genetic susceptibility to mycobacterial infection
… we identified an eQTL located in the TLR10-TLR1-TLR6 gene cluster. In non-infected macrophages, a group of polymorphisms in this region was associated in cis with the level of expression of TLR1, but not of the other two TLR genes. In M. tb-infected macrophages the same polymorphisms were …
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CANNABINOID RECEPTOR 2 AGONIST REDUCES IMMUNE CELL MIGRATION IN NEUROINFLAMMATION VIA INHIBITION OF MATRIX METALLOPROTEINASE-9
… expression of toll-like receptors (TLR1, TLR4, TLR6, and TLR7), which correlated with a decreased number of immunoreactive microglia. Interestingly, at seven days post injury, CB2R agonist-treated injured cords showed a significant reduction in both hematopoietic and myeloid cell infiltration. …