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Showing 1 to 2 of 2 for “"TLR2/9"”.

  1. Toll-like Receptors 2 and 9 Are Important for Innate Immune Cell Activation and Recruitment in Hypersensitivity Pneumonitis

    … to neutrophil recruitment. We generated TLR2/9 double knockout (TLR2/9−/− ) mice to determine the extent to which TLRs 2 and 9 cooperate in neutrophil recruitment during HP. During the acute response, TLR2/9−/− mice exposed to SR demonstrated a significant reduction in neutrophil …

    tenn-hsc Repository record for Toll-like Receptors 2 and 9 Are Important for Innate Immune Cell Activation and Recruitment in Hypersensitivity Pneumonitis (opens in a new tab)

  2. HP Turns 17: T helper 17 cell response during hypersensitivity pneumonitis (HP) and factors controlling it

    … previous studies in our lab showed that TLR2/9 double knockout (DKO) exposed mice were characterized by a decrease in the percentage of Th17 cells in their lungs compared to WT mice. Consequently, we hypothesized that the decrease in Th17 response is attributed to defect in phagocytosis, …

    tenn-hsc Repository record for HP Turns 17: T helper 17 cell response during hypersensitivity pneumonitis (HP) and factors controlling it (opens in a new tab)