Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"TLK-1"”.
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Validation of The Activation of Aurora B Kinase By Caenorhabditis Elegans to usled-Like Kinase and The Identification of Cyclin B3 As A Phospho-Specific Tlk-1 Interactor
… identified the C. elegans Tousled-like kinase (TLK-1) as an interactor and substrate activator of AIR-2. However, the role of TLK-1 kinase activity in TLK-1-promoted AIR-2 activation remained enigmatic. The research presented herein reveals that the Aurora B-activating role of TLK-1 is …
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Characterization of A Novel Role For The to usled- Like Kinase In Kinetochore Assembly and Function In Caenorhabditis Elegans
… the<em> C. elegans </em>Tousled-like kinase (TLK-1) as a mitotic kinase and depletion of TLK-1 results in embryonic lethality, characterized by nuclei displaying poor mitotic chromosome alignment, lagging chromosome, and chromosome bridges during anaphase. Additionally, previous studies from …
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Identification and Analysis of A Novel Role For The to usled-Like Kinase In Regulating Mitotic Spindle Dynamics
… Tsl and one orthologue in <em>C. elegans</em>, TLK-1, which is essential for embryonic viability and germ cell development. Depletion of TLK-1 leads to embryonic arrest large, distended nuclei, and ultimately embryonic lethality. Prior to terminal arrest, TLK-1-depleted embryos undergo aberrant …