Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 23 for “"TKR"”.
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Use of Topical (Intra-articular) Tranexamic Acid to Minimise Blood Loss and Transfusion in Total Knee Replacement Surgery
Introduction Total knee replacement (TKR) is a common orthopaedic procedure, with 20-70% of patients needing 1-3 units of blood, although allogeneic transfusion is not risk free. Tranexamic acid (TXA) is a synthetic antifibrinolytic agent used intravenously to stop bleeding in TKR and other …
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Bone mineral density changes after Total knee replacement in women over the age of 65
… female patients above 65 years old who received TKR dut to severe osteoarthritis, 52 patients who checked one year follow up BMD were enrolled. Bilaterality of operation site, degree of obesity and osteoporosis diagnosis don’t effect on BMD differences one year after TKR. But bisphosphonate …
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SPARKS: Social and Psychological Aspects of Replacement Knee Surgery - A Prospective Longitudinal Study
Background: Total Knee Replacement (TKR) surgery is typically performed to alleviate symptoms of severe, advanced osteoarthritis of the knee. TKR surgery has been shown to be an effective treatment to relieve pain and increase functional ability in the affected knee. However, after surgery a …
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Retrospective Chart Review of Patients Following Unilateral Total Knee Replacement to Assess Achievement of Functional Milestones Based on Type of Anesthetic Used Intra-Operatively
… the large number of Total Knee Replacements (TKR) performed annually in the US and the prediction that those numbers will increase, providing optimal analgesia during TKR is an important strategy for reducing cost and improving patient outcomes. Currently, no standard analgesia protocol for …
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Enhanced pre-clinical assessment of total knee replacement using computational modelling with experimental corroboration & probabilistic applications
Demand for Total Knee Replacement (TKR) surgery is high and rising; not just in numbers of procedures, but in the diversity of patient demographics and increase of expectations. Accordingly, greater efforts are being invested into the pre-clinical analysis of TKR designs, to improve their …
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Investigation of exercise, nutrition, and high tibial osteotomy interventions for patients with medial dominant knee osteoarthritis
… conversion from HTO to total knee replacement (TKR), and changes in patient-reported outcomes and gait biomechanics at 2, 5 and 10 years after HTO. We also evaluated associations between demographics and biomechanics with various clinical outcomes (i.e., responder criteria, TKR, clinically …
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An Exploration into the Relationship between Knee Shape and Kinematics Before and After Total Knee Replacement
… knee osteoarthritis. Total knee replacement (TKR) is a surgery which attempts to restore the articular shape in order to enhance function. However, the influence of implant design on kneeling kinematics is unclear. This thesis examines the role of knee shape on kneeling kinematics before and …
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An Exploration into the Relationship between Knee Shape and Kinematics Before and After Total Knee Replacement
… knee osteoarthritis. Total knee replacement (TKR) is a surgery which attempts to restore the articular shape in order to enhance function. However, the influence of implant design on kneeling kinematics is unclear. This thesis examines the role of knee shape on kneeling kinematics before and …
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Understanding changes in plant productivity using EVI satellite data in Tswalu Kalahari Reserve
… in the 100 000 hectare Tswalu Kalahari Reserve (TKR) in the semi-arid Northern Cape and relate the observed changes to potential drivers using medium spatial resolution of MODIS Enhanced Vegetation Index (EVI) time series data (16 day, 250 m) from 2000 to 2015. The time series of EVI for the past …
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Wear of ultra-high molecular weight polyethylene manufactured with laser powder bed fusion
More than 750,000 total knee replacement (TKR) surgeries are performed annually in the United States (US) to treat degenerative joint diseases such as osteoarthritis. A prosthetic knee implant typically comprises a cobalt chromium (CoCr) femoral component and a polyethylene tibial insert that is …
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Osteoarthritis. Epidemiologic and genetic aspects.
… replacement (THR) and total knee replacement (TKR) due to osteoarthritis (OA), (II) assess the association between the mechanical load of work and THR and TKR due to OA, (III) evaluate the natural history of radiographic hip OA with regards to THR and hip fracture, (IV) to determine the …
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A Randomized Controlled Trial to Establish Realistic Patient Expectations Following Total Knee Replacement Surgery
… 1 year following primary total knee replacement (TKR) (Chapter 3). In Chapter 4, we described characteristics of users and utilization patterns of the e-learning tool. In Chapter 5, we evaluated the internal consistency and construct validity of the new Knee Society Knee Scoring System (KSS) in a …
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Patient Movement Monitoring Based on IMU and Deep Learning
… (OA) and total knee replacement patients (TKR) through a detailed biomechanical assessment and development of machine learning algorithms. Specifically, the first study developed a relevant dataset consisting of IMU and associated biomechanical parameters of OA and TKR patients performing …
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Three Dimensional CT based Virtual Patellar Resection in Female Patients undergoing Total Knee Replacement
… of knees from 49 patients who underwent primary TKR at our hospital, comparing two commonly used resection methods, i.e., the tendon method (TM), and the subchondral method (SCM), to determine an ideal resection plane with respect to the symmetry and thickness of the patellar remnant. Results: …
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Research into the Design and Validation of an Innovative Intraoperative Load Sensor for Total Knee Replacements through Experimental and Cadaveric Investigations
… the knee joint during a Total Knee Replacement (TKR) is a vital parameter for surgeons to achieve successful outcomes for patients due to the complexity of the joint, articulating surfaces, tendons, and ligaments. These structures are all impacted by the forces created in the joint following a …
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Statistical Modeling to Investigate Anatomy and Function of the Knee
… bone of a subject with a total knee replacement (TKR) was evaluated by a statistical shape model of the patella and simulated 2D edge profiles in a custom optimization algorithm. Lastly, a validated predictive algorithm was employed to assess the accuracy of subject-specific knee articular …
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Investigation of a heirarchical collagen scaffold/3D printed lattice structure designed for use in total knee replacements
… of late-stage failure in total knee replacement (TKR) surgery. This multifactorial condition is exacerbated by stress shielding and micromotion at the bone/implant interface. Stress shielding can be reduced using implant materials with a similar modulus to that of the surrounding bone, such as …
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Behavioural and Metabolic Characterization of NPR-9 and AIB Signaling Dynamics in Caenorhabditis Elegans
… chloride channel MOD-1, and tachykinin GPCR TKR-2 also regulates lipid metabolism, likely via the control of glutamate release. In the context of the locomotory circuit, glutamate release inhibits inter/motor neuron RIM via inhibitory glutamate gated chloride channel receptor AVR-14. …
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Validation and Analysis of Model-Predicted Patellar Implant-Synthetic Bone Relative Motion in Cementless Total Knee Replacement During a Single-Leg Lunge
… stability of cementless total knee replacement (TKR) components is crucial to establish bony ingrowth into the porous interface surface and long-term fixation, however, few cementless patellar implant micromotion tests have been developed. Previous studies were all focused on qualifying tibial …
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Prediction of knee loading in native knee and total knee arthroplasty : a forward dynamics computational study
… in vivo measurements from the instrumented TKR for three distinctly different styles of over ground gait. (2) Virtual surgery in TKA: The musculoskeletal modeling methodology was then used to develop a model for one healthy participant with a native knee and then virtually replacing the …
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