Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 194 for “"THR"”.
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Poly(β-Gal-Thr): A New Scalable Synthetic Mucin
… of 2,3,4,6-tetraacetyl-<em>β</em>-galactose-threonine <em>N</em>-carboxyanhydride (<em>β</em>-AcO-Gal-Thr-NCA) monomer in 5 steps with an 8 % overall yield is described, and the single-crystal X-ray structure is provided. The effect of a series of Ni<sup>0</sup>-based organometallic …
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Structural Basis of Signal Transduction within Environmental Sensing PAS Regulated Ser/Thr Kinases
… and kinase domains. These changes propagated through Ja-LH1-LH2 linkers, connecting LOV2 to the STK domain and highlighting the role of the n-lobe of the STK in mediating these interactions with the LOV2 domain. Additionally, our <strong>C</strong>ryo-<strong>E</strong>lectron …
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Computational structure analysis and prediction of Ser/Thr modified by O-GlcNAc in human proteins
… O-GlcNAcylation, targets specific Serines and Threonines (S/T) of intracellular proteins. However, while other post-translationally modified residues, including phosphorylated ones, occur within sites distinguished by their amino acid sequences, less than 25% of known O-GlcNAc sites match to a …
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Mutagenic Studies of RdoA, a Eukaryotic-Like SER/THR Protein Kinase in Salmonella Enterica Serovar Typhimurium
RdoA is a eukaryotic-like serine/threonine protein kinase found in Salmonella typhimurium. It is a downstream effector of the Cpx stress response pathway and has been phenotypically characterized to have a functional role in flagellin phase variation and long-term bacterial survivability. …
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Adaptation des architectures ADDA et semi-ADDA pour la détection d'objets par apprentissage profond sur les images satellites THR
La détection d’objets est une tâche fondamentale en vision par ordinateur ayant pour but d’identifier et de localiser différentes catégories d’objets dans une image selon une taxonomie prédéfinie. Entraînées par l’émergence des réseaux de neurones convolutifs (CNNs, convolutional neural networks), …
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Comprehensive definition of Ser/Thr/Tyr phosphorylation in mycobacteria: towards understanding reprogramming of normal macrophage function by pathogenic mycobacteria
… regulation by the process of phosphorylation, through sensory kinases, which add a phosphate group to a protein of interest, thereby regulating its function. First, we interrogated the phosphoproteomic landscape between M. bovis BCG and M. smegmatis to explain how differential protein …
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Modulation of Alpha-Subunit VISIT-DG Sequence Residues Ser-347, Gly-351 and Thr-349 in the Catalytic Sites of <em>Escherichia coli</em> ATP Synthase.
… sequence residues αSer-347, αGly-351, and αThr-349 in P<sub>i</sub> binding. Mutations αS347A/Q, αG351Q, αT349A/D/R, βR182A, and αT349R/βR182A were generated via site directed mutagenesis. Results from biochemical assays showed that αSer-347 is required for transition state stabilization …
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Effects of Supplementing Crystalline L-Valine and L-Isoleucine and a Novel Threonine Biomass in Reduced Crude Protein Diets fed to Broilers
… supplemented in addition to L-Met, L-Lys, and L-Thr to further reduce dietary CP in corn and SBM-based diets. Peanut meal or animal protein blend was used to replace partial amounts of SBM. Results confirmed that broilers maintained performance when fed reduced CP diets, independent of diet …
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INTERACTIVE EFFECT OF DIETARY FIBRE AND IMMUNE CHALLENGE ON THREONINE REQUIREMENT AND INTESTINAL BARRIER FUNCTION IN GROWING PIGS
… deposition (PD) and growth in pigs. Fibre and threonine (Thr) may also play an important role in intestinal barrier function. Therefore, this thesis evaluated the independent and combined effects of high DF and immune challenge [Salmonella typhimurium and systemic E. coli lipopolysaccharide …
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The combined effects of purified fiber and dietary threonine on chick growth, and gut health, when infected with coccidiosis
Three experiments were conducted to determine the combined effects of purified dietary fiber and dietary threonine (Thr) on chick growth and intestinal health. The objectives of the first two experiments were to define the individual effect of purified fiber on nutrient digestibility, dietary Thr …
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Dietary guanidino acetic acid spares arginine and dietary l-homoserine spares threonine in the chick
… as an intermediate compound in the metabolism of Thr, Met, and Asp. Bacteria, plants and yeast can synthesize Thr and Met from HS, but this has not been shown in higher organisms. Several bioassays were carried out to determine the capacity of GAA to spare dietary Arg or HS to spare dietary Thr. …
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Die Funktion von Three rows bei der Schwesterchromatiden-Trennung in Drosophila melanogaster
… SSE einen heterotrimeren Komplex mit dem Protein Three rows (THR) bilden. THR besitzt Bindungsstellen für PIM und SSE. In anderen Organismen besitzt die N-terminale Separase-Domäne Bindungsstellen für das Securin und die Protease-Domäne der Separase. Diese Ergebnisse legen nahe, dass THR …
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Role of Protein Kinase C Zeta (PKCζ) in Regulation of Epithelial Tight Junctions
<p>Occludin is hyperphosphorylated on Ser and Thr residues in intact epithelial tight junctions. The dynamics of epithelial tight junctions appear to involve reversible phosphorylation of occludin on Ser and Thr residues. In the present study we determined the role of PKCζ in occludin …
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Determination of the Binding Site and the Key Amino Acids on Maize β-Glucosidase Isozyme Glu1 Involved in Binding to β-Glucosidase Aggregating Factor (BGAF)
… that a region spanning 11 amino acids (Ile⁷²-Thr⁸²) on Glu1 is essential and sufficient for BGAF binding, whereas the extreme N-terminal region Ser¹-Thr²⁹, together with C-terminal region Phe⁴⁶⁶-Ala⁵¹², affects the size of Glu1-BGAF complexes. To determine the importance of each region for …
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Protein-protein interaction between multi-functional protein CAD and protein phosphastase 1 (PP1)
… multifunctional protein that catalyzes the first three steps in pyrimidine biosynthesis. The cell cycle dependent regulation of pyrimidine biosynthesis is a consequence of sequential phosphorylation of CAD Thr-456 and Ser-1406 by the MAP kinase and PKA cascades, respectively. The mechanism that …
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Effects of fiber on the optimum threonine:lysine ratio for 25 to 50 kg growing gilts
… were conducted to determine the ideal Thr:Lys ratio for 25 to 50 kg growing gilts and the effects of fiber on said ratio. In Exp. 1, the objectives were to determine the standardized ileal digestible (SID) Lys requirement for gilts from 25 to 50 kg BW. Seventy gilts (initial BW: 24.54 ± …
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The Psychosocial and Physical effects of Therapeutic Horseback Riding for Children with Cerebral Palsy
… activities such as therapeutic horseback riding (THR) is critical for children with cerebral palsy (CP) as they are at increased risk for lower habitual physical activity levels, social exclusion and mental health conditions. The benefits of THR for children CP are unclear despite positive …
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Development of an optimum acetabular cup prosthesis
… trend of performing Total Hip Replacements(THR) on younger patients incurs an increasing number of revisions. Therefore, prolonging the life of a THR is of paramount importance and is the principal goal of this study. With this trend comes a new set of design goals driven by higher patient …
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Examining Sex Differences in Substrate Utilization During Threshold-Based Exercise Prescription
… linked to sex-based differences in lactate threshold (LT) and critical power (CP). Thus, the purpose of this thesis was to examine the effect of threshold-based exercise prescribed (THR) using LT and CP to determine whether using THR – specifically, an intensity anchored halfway between LT …
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Acetabular Component Migration Following Revision Total Hip Replacement
… component after total hip replacement (THR) is loosening. Identifying a surrogate, such as early migration, that could predict the long-term performance of revision acetabular components and techniques is important given the introduction of new implants and techniques. Radiostereometric …
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