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Showing 1 to 20 of 168 for “"TGF-beta"”.

  1. TGF-beta signaling at the cellular junctions

    Dudu, VeronicaTechnische Universität Dresden

    … I have studied transforming growth factor-beta (TGF-beta) signal from the secreting to the receiving cells in the developing wing epithelial cells and at the neuromuscular junctions. Cell culture studies have suggested that cells modulate morphogenetic signaling by expressing the receptors …

    qucosa-diss

  2. Involvement of TGF-beta in skin photoaging

    Choi, Won Seon, 1975-Massachusetts Institute of Technology2005

    … this thesis study was to understand the role of TGF-[beta] in skin photoaging, especially in solar elastosis. Solar elastosis, the accumulation of elastotic material in the dermal extracelluar matrix, is a major hallmark of photoaging. However, the mechanisms by which UV radiation causes solar …

    mit Repository record

  3. TGF-beta und Empfindlichkeit für NO-abhängige Apoptose

    Moosmann, Nicolas

    … apoptotischen Zelltod induzieren. Dabei spielt TGF-beta eine zentrale Rolle. 48-stündige Einwirkung von TGF-beta auf nicht-transformierte NRK-Fibroblasten steigert deren normalerweise niedrige Empfindlichkeit gegenüber NO. 208 F Fibroblasten lassen sich nicht gegenüber der Apoptoseinduktion …

    freiburg-diss Repository record

  4. Einfluss von Transforming Growth Factor-beta1 (TGF-[beta]1) Genpolymorphismen auf die Hepatitis-C-induzierte Leberfibrose in vivo und Modulation der TGF-[beta]1-Synthese, Prozessierung und Sekretion durch die Serin-Protease Furin, das latent TGF-[beta] binding protein-1 und Polymorphismen der TGF-[beta]1-Signalsequenz in vitro

    Mohren, SimonePublikationsserver der RWTH Aachen University2008

    … the first part of this thesis, the influence of TGF-beta1 polymorphisms at position –509, codon 10, codon 25 and codon 263 on hepatitis C induced liver fibrosis was analysed. For that purpose, liver needle biopsies from 430 patients suffering from chronic hepatitis C infection were scored for the …

    aachen Repository record

  5. Untersuchungen zur TGF-[beta]1-Signaltransduktion in kultivierten hepatischen Sternzellen : Einfluss auf DNA-Synthese und subzelluläre Lokalisation des Alk5 TGF-[beta]-Rezeptors

    Purps, Oliver2006

    aachen Repository record

  6. TGF-beta 1 PATHWAY AND AGE-RELATED MACULAR DEGENERATION

    FISICHELLA, VINCENZOUniversità degli studi di Catania2017

    … macular degeneration (AMD) using amyloid-beta (Abeta) oligomers, and assess the effect of TGF-beta 1. Furthermore a topical formulation of transforming growth factor 1 (TGF-beta 1) was developed; and TGF-beta 1 ocular pharmacokinetics profile was assessed. Methods: Sprague-Dawley male rats …

    catania Repository record

  7. Knochenneubildung durch induktive Implantate der TGF-Beta-Familie : eine tierexperimentelle Studie zum Synergismus von BMP-2-Mutanten und TGF-Beta bei der heterotopen Osteoinduktion

    Janke, Carsten Theodor WilhelmUniversität Würzburg

    … Einfluss des Faktors „Transforming growth factor beta 1“ auf das physiologische Remodelling des Knochens sind durch zahlreiche In-vitro- und In-vivo-Untersuchungen belegt. Die gentechnische Modifikation der N-terminalen Aminosäuresequenz von rekombinantem, im bakteriellen System (E. coli) …

    wurz-thes Repository record

  8. Die Entwicklung der Pankreasfibrose im TGF-beta-1-transgenen Tiermodell

    Ruf, Doris AnneUniversität Ulm

    ulm-diss Repository record

  9. TGF-beta in chronic sinus diseases: from immuneregulation to remodeling

    VAN BRUAENE, NICHOLASGhent University. Faculty of Medicine and Health Sciences2012

    ghent Repository record

  10. Expressionsanalyse von Mediatoren der TGF-[Beta]-Signalkaskade in Lebersternzellen und Myofibroblasten

    Marquardt, Eva Maike2003

    aachen Repository record

  11. Untersuchungen zur Rolle von TGF-[Beta] in der Differenzierung von Teratokarzinomzellen

    Preuß, Natalie1996

    aachen Repository record

  12. Untersuchungen zur TGF-[beta]1-Expression und -Bioverfügbarkeit bei der Leberfibrogenese

    Westhoff, Jens HendrikPublikationsserver der RWTH Aachen University2005

    Transforming growth factor-Beta (TGF-Beta) is one of the most important cytokines mediating fibrogenesis in the liver and in other organs. The major portion of it is secreted as latent molecule complexed either only with the “latency associated peptide” (LAP) or with LAP and the “latent TGF-Beta …

    aachen Repository record

  13. TGF-beta,Smad signaling in hepatic stellate cells and during liver fibrogenesis

    Wiercinska, ElizaPublikationsserver der RWTH Aachen University2005

    Transforming growth factor (TGF)-beta is a key mediator of hepatic stellate cell (HSC) activation and extracellular matrix accumulation leading to fibrosis. Aim of the present study was to perturb the TGF-beta pathway in this process by overexpression of Smad7, an intracellular antagonist of …

    aachen Repository record

  14. Expressionsstudien und Mutationsanalyse des TGF-[beta]-Antagonisten Smad7 in menschlichen hepatozellulären Karzinomen

    Bauche, Britta EllenPublikationsserver der RWTH Aachen University2005

    Members of the transforming growth factor Beta (TGF-Beta) family transmit signals from membrane to nucleus via intracellular proteins known as Smads. After binding of TGF-Beta to the receptor complex (consisting of TGF-Beta receptor I and II), Smad2 and/or Smad3 are activated by phosphorylation …

    aachen Repository record

  15. TGF-beta Activated Kinase-1 (TAK1) Is a Critical Prostate Tumor Suppressor

    Wu, MinWake Forest University2011

    TGF-beta activated kinase-1 (TAK1) encoded by the MAP3K7 gene is a serine/threonine protein kinase that functions in the regulation of cell proliferation, apoptosis, differentiation and/or inflammation. Genetic studies have shown that hemizygous deletion of the MAP3K7 gene is frequent (32%) in …

    wfu Repository record

  16. Isolierung, Charakterisierung und Funktionsanalyse von TGF-Beta-Signaltransduktionskomponenten des Fuchsbandwurms Echinococcus multilocularis

    Zavala Góngora, RicardoUniversität Würzburg

    … zur Steuerung von Entwicklungsvorgängen ist das TGFβ/BMP-System, das aus strukturell verwandten Zytokinen der TGFβ (transforming growth factor β) bzw. BMP (bone morphogenetic protein)-Familie, oberflächenständigen Rezeptoren der TGFβ-Rezeptorfamilie (Typ I und Typ II) und intrazellulären …

    wurz-thes Repository record

  17. Phosphorylation and activation of transforming growth factor beta (TGF-[beta]) receptor kinases

    Chen, FengMassachusetts Institute of Technology1996

    Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1996.

    mit Repository record

  18. Genexpressionsmuster nach Behandlung von Hepatomzellen mit dem Cytokin TGF-beta bzw. mit Tumorpromotoren

    Herckelrath, Tanja2004

    tuebingen

  19. Modulation of TGF-beta and extracellular matrix in retionic acid-induced cleft palate

    Degitz, Sigmund Jay, Jr.University of Illinois at Urbana-Champaign2011

    The morphologic findings of altered mesenchymal organization and delayed elevation of the palatal shelves indicate RA-induced changes in palatal shelf extracellular matrix. The patterns of localization of collagen I, III, and IV, fibronectin, tenascin, laminin and hyaluronate were investigated in …

    uiuc Repository record

  20. Interaktion zwischen TGF-[beta]-Smad-3 und dem Glukokortikoidrezeptor vermittelten Signalweg in hepatischen Sternzellen

    Bolkenius, Ursula2005

    aachen Repository record

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