Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"TGF-ß-signaling"”.
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Identifikation und Charakterisierung von Interaktionspartnern des Zystennierenproteins DZIP1L
… the pronephros and plays a role in the hedgehog signaling pathway. Term of this doctoral thesis was the identification of interaction partners of DZIP1L by a bacterial Two Hybrid system to further characterize the function and role of the protein in the cell. Coimmunoprecipitation experiments and …
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Identifying the Molecular Mechanism of TAZ-Induced Lung Tumorigenesis
… FGFs, etc. Interestingly, we identified PI3K and TGF-ß signaling pathways as mediators of TAZ-induced cell proliferation and transformation, which were inhibited by using small molecule inhibitors specifically targeting these two signaling pathways. In addition, TAZ-induced cell proliferation and …
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Spatio-temporal investigation and quantitative analysis of the BMP signaling pathway
… in the developing embryos. Using the diverse signaling input information within the embryo due to the gradient, the cells transduce the varying extracellular information into distinct gene expression profiles and cell fate decisions. Furthermore, BMP proteins bear important functions in adult …