Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"TGF-¿3"”.
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Cell engineering of human bone monolayers and the effect of growth factors and microcontact printed ECM proteins on wound healing. The role of ECM proteins, TGF¿-1, 2 and 3 and HCl/BSA in cellular adhesion, wound healing and imaging of the cell surface interface with the widefield surface plasmon microscope.
… that the Transforming Growth Factor-beta (TGF-¿) super-family of cytokines have significant effects on bone structure by regulating the replication and differentiation of chondrocytes, osteoblasts and osteoclasts. There is also significant evidence that interactions with extracellular …
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Bone morphogenetic proteins (BMPs): new modulators of the follicle stimulating hormone (FSH) synthesis and release
… members of the Transforming Growth Factor -Beta (TGF -(3) superfamily, inhibit and stimulate respectively FSH synthesis and release. These gonadal factors are also produced in the pituitary where they act as paracrine factors. Other molecules of the TGF -13 superfamily, the Bone Morphogenetic …
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Tumour suppression mediated through DPC4, p53 and APC
… Second, it examines the in vitro effects of TGF -ß signalling, of which SMAD4 is the central mediator, on murine primary cultured pancreatic acinar cells. Previously p53 ApcM "i+ mice have been shown to develop pancreatic tumours. To examine the effect of Smad4 heterozygous mutation on the …
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Investigating the use of omega three fish oils as protective agents against cytokine-induced skeletal muscle damage
… via suppression of TransformingGrowth Factor-Pi (TGF-pi,Das 2004). Our group showed ERA protection fromcytokine (TNFa) induced muscular atrophy in a murine cell model (Magee et al2008). Further, ERA may have intracellular signaling component interactions and bedependent on PPARy (Magee et al …
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Roles for the E3 Ligase Itch in Immune Response Modulation
… sensitivity to the immunomodulatory cytokine TGF-(3 was reduced in Itch deficient CD4+ T cells. Inadequacies in peripheral tolerance mechanisms were observed based on oral tolerance studies. Itch deficiency was found to directly contribute to the CD4+ bias towards T helper type-2 (Th2) …
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The Isolation and Characterization of Growth Regulatory Factors Produced by a Herpes Simplex Virus Type 2 Transformed Mouse Tumor Cell Line, H238
… and resembles transforming growth factor-^ (TGF-/3); the second bound to lectin-coated sepharose beads and was sensitive to trypsin, neuroaminidase, and the reducing agent dithiothreitol (DTT) and, resembled a platelet-derived growth factor (PDGF)-like factor; and the third displaced [ …
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Self-assembling peptide hydrogels promote in vitro chondrogenesis of bone marrow-derived stromal cells : effects of peptide sequence, cell donor age, and method of growth factor delivery
… BMSCs in all three hydrogels underwent TGF-3 1-mediated chondrogenesis as demonstrated by comparable gene expression and ECM biosynthesis. Cell proliferation occurred only in the peptide hydrogels, not in agarose, resulting in higher sulfated-glycosaminoglycan content and more spatially …
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Cell and tissue engineering of articular cartilage via regulation and alignment of primary chondrocyte using manipulated transforming growth factors and ECM proteins. Effect of transforming growth factor-beta (TGF-¿1, 2 and 3) on the biological regulation and wound repair of chondrocyte monolayers with and without presence of ECM proteins.
… Transforming growth factor-beta (TGF-¿), a cytokine superfamily, regulates cell function, including differentiation and proliferation. The effect of TGF-¿1, 2, 3, and their manipulated forms in biological regulation of primary chondrocyte was investigated in this work. A novel …
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Cell and tissue engineering of articular cartilage via regulation and alignment of primary chondrocyte using manipulated transforming growth factors and ECM proteins. Effect of transforming growth factor-beta (TGF-¿1, 2 and 3) on the biological regulation and wound repair of chondrocyte monolayers with and without presence of ECM proteins.
… Transforming growth factor-beta (TGF-¿), a cytokine superfamily, regulates cell function, including differentiation and proliferation. The effect of TGF-¿1, 2, 3, and their manipulated forms in biological regulation of primary chondrocyte was investigated in this work. A novel …
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Cell and tissue engineering of articular cartilage via regulation and alignment of primary chondrocyte using manipulated transforming growth factors and ECM proteins. Effect of transforming growth factor-beta (TGF-¿1, 2 and 3) on the biological regulation and wound repair of chondrocyte monolayers with and without presence of ECM proteins.
… Transforming growth factor-beta (TGF-¿), a cytokine superfamily, regulates cell function, including differentiation and proliferation. The effect of TGF-¿1, 2, 3, and their manipulated forms in biological regulation of primary chondrocyte was investigated in this work. A novel …