Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"TGF-¿1"”.
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An investigation into the role of TBX3 in breast carcinogenesis and its regulation by the TGF-?1 signalling pathway
… and migration and that its upregulation by the TGF-β1 signalling pathway mediates the TGF-β1-regulated anti-proliferative and pro-migratory effects. Furthermore, this study demonstrates that TBX3 mediates the anti-proliferative function of TGF-β1 through repressing transcription of its …
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Cell engineering of human bone monolayers and the effect of growth factors and microcontact printed ECM proteins on wound healing. The role of ECM proteins, TGF¿-1, 2 and 3 and HCl/BSA in cellular adhesion, wound healing and imaging of the cell surface interface with the widefield surface plasmon microscope.
… that the Transforming Growth Factor-beta (TGF-¿) super-family of cytokines have significant effects on bone structure by regulating the replication and differentiation of chondrocytes, osteoblasts and osteoclasts. There is also significant evidence that interactions with extracellular …
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Cell and tissue engineering of articular cartilage via regulation and alignment of primary chondrocyte using manipulated transforming growth factors and ECM proteins. Effect of transforming growth factor-beta (TGF-¿1, 2 and 3) on the biological regulation and wound repair of chondrocyte monolayers with and without presence of ECM proteins.
… Transforming growth factor-beta (TGF-¿), a cytokine superfamily, regulates cell function, including differentiation and proliferation. The effect of TGF-¿1, 2, 3, and their manipulated forms in biological regulation of primary chondrocyte was investigated in this work. A novel …
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Cell and tissue engineering of articular cartilage via regulation and alignment of primary chondrocyte using manipulated transforming growth factors and ECM proteins. Effect of transforming growth factor-beta (TGF-¿1, 2 and 3) on the biological regulation and wound repair of chondrocyte monolayers with and without presence of ECM proteins.
… Transforming growth factor-beta (TGF-¿), a cytokine superfamily, regulates cell function, including differentiation and proliferation. The effect of TGF-¿1, 2, 3, and their manipulated forms in biological regulation of primary chondrocyte was investigated in this work. A novel …
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Cell and tissue engineering of articular cartilage via regulation and alignment of primary chondrocyte using manipulated transforming growth factors and ECM proteins. Effect of transforming growth factor-beta (TGF-¿1, 2 and 3) on the biological regulation and wound repair of chondrocyte monolayers with and without presence of ECM proteins.
… Transforming growth factor-beta (TGF-¿), a cytokine superfamily, regulates cell function, including differentiation and proliferation. The effect of TGF-¿1, 2, 3, and their manipulated forms in biological regulation of primary chondrocyte was investigated in this work. A novel …
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The Fumonisin B1-Fed Rat as a model for liver injury, oval Progenitor') cell proliferation, and carcinogenesis
… in the expression of mRNA transcripts for mature TGF-~ 1 and c-myc in livers ofFB1-fed animals. The overexpression of TGF-~ 1 by hepatocytes may be responsible for the prominent apoptosis and fibrosis seen with liver injury due to FB1. Increased expression of c-myc and TGF-~ 1 may cooperate during …
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Development of a novel cell traction force transducer based on cholesteryl ester liquid crystals. Characterisation, quantification and evaluation of a cholesteryl ester liquid crystal based single cell force transducer system.
… using a known pharmacological active cytokine, TGF-¿1, in inducing contraction of human keratinocytes. This study inferred internal consistency and repeatability of the LCTFT in sensing contraction responses of HaCaT cells in a concentration dependent manner of TGF-¿1. The overall LCTFT and CTFM …
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Assoziation zwischen vier Polymorphismen des menschlichen Transforming-Growth-Factor-beta1-Gens und der zeitlichen Progression der posthepatitischen Leberfibrose
… relationships between four polymorphisms of the TGF-beta1 gene (-800G>A; -509C>T; Leu10Pro; Arg25Pro) and stage, histological activity grade and progression rate (METAVIR-score) of liver fibrosis. Methods: Three study groups, i.e. 48 patients with hepatic fibrosis (26 with known duration of …
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EFFECT OF COMBINATION OF THE MAMMALIAN LIGNAN, ENTEROLACTONE, WITH TYROSINE KINASE INHIBITORS ON MARKERS OF HEPATIC FIBROSIS
… antifibrotic effects of ENL and/or gefitinib in TGF-1-stimulated LX-2 cells. The combination of gefitinib and ENL attenuated the fibrotic biomarkers to a greater extent than using each compound alone. In further experiments evaluating reactive oxygen species (ROS) production, caspase-3/7 …
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Untersuchungen zu Auswirkungen von GAG-Linkeropathien auf die ECM-Homöstase durch die Generierung von knockout-Modellen in Dermalfibroblasten
… durch das Zytokin TGF1 induziert wurde. Zusammengefasst konnten im Rahmen dieser Arbeit vielversprechende Modelle zum besseren Verständnis der Pathologie von GAG-Linkeropathien entwickelt werden. Die kurzfristige, sowie auch die langfristige Defizienz von …
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Snail1-mediated Gene Repression Links EMT to Enhanced Biliary Epithelial Cell Survival and Lung Epithelial Cancer Cell Migration
… we utilized transforming growth factor-beta 1 (TGF-β1) to establish EMT in non-malignant murine biliary epithelial cells (cholangiocytes, 603B cells) and human lung epithelial carcinoma cells (A495 cells). We examined collagen production and cell survival in 603B cells and cell migration in A549 …