Global ETD Search
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Showing 1 to 3 of 3 for “"TFIIIB"”.
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Extra-Transcriptional Effects of Chromatin Bound RNA Polymerase III Transcription Complexes
… A-box and B-box and aids the assembly of TFIIIB to upstream of the transcriptional start site. Upon binding, Pol III is recruited near start sites and transcription of tRNA genes is initiated. Apart from transcription of a gene, these bound Pol III complexes influence transcription, …
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Regulation of mammalian SINE transcription
… were found to be bound by transcription factors TFIIIB and TFIIIC at comparable levels with actively transcribed genes. Some RNA polymerase III was also detected, but at levels significantly lower than on active genes, suggesting a defect in RNA polymerase III loading onto SINEs. This occupancy …
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STRUCTURAL INSIGHTS INTO RNA POLYMERASE III PRE-INITIATION COMPLEX AND THE PIONEER ROLE OF OCT1
Despite the central role of small non-coding RNAs in RNA metabolism and gene regulation, the mechanisms by which RNA polymerase III (Pol III) is selectively recruited to snRNA promoters remain poorly understood. This is particularly notable because Pol II- and Pol III-transcribed snRNA promoters …