Global ETD Search
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Showing 1 to 6 of 6 for “"TFIIA"”.
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New sides of an old factor: TFIIA function and regulation
Contains fulltext : 27006.pdf (Publisher’s version ) (Open Access)
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Preinitiation Complex Assembly and General Transcription Factor IIA
… the formation of complexes including TFIID, TFIIA, and TFIIB. To further the study of this complex, attention is then turned to TFIIA. A eDNA is isolated encoding the small subunit of TFIIA from Drosophila melanogaster. The protein encoded by this eDNA, dTFIIA-S, is highly homologous to the …
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Charakterisierung des negativen Cofaktors 2 der RNA-Polymerase II in vivo und in vitro
… Anlagerung der generellen Transkriptionsfaktoren TFIIA und TFIIB und führt dadurch zur Unterbrechung der Bildung des Initiationskomplexes. NC2 besteht aus zwei Untereinheiten, NC2a und NC2b, die starke Homologien zu den Histonen H2A bzw. H2B aufweisen. Alle Erkenntnisse zu Beginn dieser Arbeit …
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GENOME-WIDE PROTEIN MOLECULAR ARCHITECTURE OF HUMAN PROMOTERS
… into a transcriptionally paused state, TBP and TFIIA show significantly higher occupancy at TATA-like core promoters compared to TATA-less core promoters. Additionally, we discovered that genome-wide +1 nucleosomes exhibit a stable in vivo architecture, with paused Pol II embedded within these …
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Transcriptional Regulation Mediated by Human Papillomavirus E2 Protein
… factors and general cofactors, such as TAFIIs, TFIIA, Mediator, and PC4, were found not to be required for E2-mediated repression. HPV E2 is able to directly target components of the general transcription machinery to exert its repressor activity on the natural HPV E6 promoter. These results …
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Regulation of transcription in Plasmodium falciparum, the causative agent of severe malaria: initial characterisation of PfTBP and PfTFIIA
… and function of P. falciparum TBP, TLP and TFIIA, key proteins involved in core promoter recognition, the first step in RNAP-II transcription initiation complex assembly. The work provides strong evidence for the existence of two different PfTFIIA complexes containing different PfTFIIA-γ …