Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"TFE3"”.
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MIT/TFE FACTORS CONTROL ER-PHAGY VIA TRANSCRIPTIONAL REGULATION OF FAM134B
… responsive transcription factors TFEB and TFE3—master regulators of lysosomal biogenesis and autophagy—control ER-phagy by inducing the expression of the ER-phagy receptor FAM134B. The TFEB/TFE3-FAM134B axis is activated in chondrocytes by FGF signalling, a critical regulator of skeletal …
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Estudio de la regulación de la dinámica de localización subcelular de HLH-30: evidencia de un mecanismo dependiente de redox
Los factores de transcripción TFEB y TFE3 son los principales reguladores de la inducción de la autofagia y la biogénesis lisosomal en mamíferos. En condiciones de crecimiento basal, la fosforilación de un residuo de serina clave, S211 en TFEB y S321 en TFE3, por la quinasa mTORC1, permite la …
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Mechanism and Functions of STING-Induced Noncanonical Autophagy
… of MiT/TFE transcription factors (TFEB, TFE3, and MITF), promoting endolysosomal biogenesis. Furthermore, we showed that STING-induced noncanonical autophagy induces ALIX-meditated ESCRT machinery recruitment to mitigate endolysosomal perturbation. Our study unraveled the multifaceted …
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The interconnected KIT receptor and Microphthalmia-associated transcription factor axis in melanoma
… of MITF towards TFEB, TFEC and TFE3, the binding of M-box DNA sequence and the ability to produce interallelic complementation. In short, the detailing of KIT and MITF regulation has increased our understanding of key signaling processes that are important to understand the …
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Genetic and molecular factors regulating growth and morphology in Senegalese sole (Solea senegalensis)
… differentially expressed (pptc7, taz, abcd1, tfe3, nfix, ptcd2, prkaa1), and related to mitochondrial homeostasis and activity, energy production, and musculoskeletal system. Altogether, these results have important implications for improving productivity, commercialization, and sustainability …