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Showing 1 to 20 of 40 for “"TEER"”.

  1. Development of an Integrated Microfluidic and TEER Measurement System for Static and Dynamic Blood–Brain Barrier Models

    Rouhani, Tariq IhsanStellenbosch : Stellenbosch University2026

    … Electrical Resistance (TEER) to monitor barrier integrity. This project aimed to develop a multi-channel TEER measuring system that could interface with both static transwell models and custom microfluidic devices with the aim of creating a dynamic testing platform for …

    stellenbosch Repository record

  2. Role of matriptase in the regulation of epithelial barrier permeability studied using MDCK cells

    Elghadban, SalmaUniversity of East Anglia2014

    … rements!of!transepithelial!electrical!resistance!(TEER).! Inhibitors!of!matriptase!proteolytic!activity!delayed!the!restoration!of!TEER!after! calciumNswitch! in!MDCKNI,! which! develop! high! TEER! and! lack! the! “leaky”! tight! …

    east-anglia Repository record

  3. Development of in vitro infant intestinal models to assess responses to infant formulae

    Bietto, FrancescaUniversity College Cork2025

    … reduced transepithelial electrical resistance (TEER) and increased paracellular permeability of Caco-2 monolayers in a dose-dependent manner under hyperosmotic conditions. NaB uptake occurred via monocarboxylate transporters (MCT-1, SMCT-1). However, NaB caused elevated apoptosis (Caspase-3 …

    cork Repository record

  4. Probiotic Modulation of Mucosal Immune Responses in an In Vitro Co-Culture Model

    Habil, Neama2013

    … included cytokine, TLR and hBD-2 expression, TEER and IHC staining of the tight junction protein, ZO-1. Probiotics selectively modulated monocyte and macrophage subset cytokine expression. Probiotics (HK and SP) suppress CD14 lo , augment CD14 hi M1, and differentially regulated TNF-α …

    plymouth Repository record

  5. A microphysiological system for studying barrier health of live tissues in real time

    Way, Ryan, author, Chen, Thomas W., advisor, Wilson, Jesse, committee member, Chicco, Adam, committee memberColorado State University. Libraries2024

    … transepithelial electrical resistance (TEER); and a scalable system architecture to allow multiple chambers running in parallel for increased throughput. The experimental results demonstrate that the system can maintain tissue viability for up to 72 hours. The results also show that the …

    colostate Repository record

  6. Modelling the gastric epithelium for testing of new chemical entities

    Kavvada, Klairi M.Aston University2004

    … by measurement of transepithelial resistance (TEER) and permeability of mannitol and fluorescein. Coating the polycarbonate filter with collagen IV, rather with collagen I, enhanced tight junction formation. TEER for cells grown on Transwells coated with collagen IV was close to that obtained …

    aston Repository record

  7. Establishment of a Novel Patient hiPSC-derived in vitro Blood-Brain Barrier Model of Collagen IV Small Vessel Disease

    Goodwin-Trotman, MaryUniversity of Cambridge2020

    … transendothelial electrical resistance (TEER), permeability assays (4kDa FITC-Dextran and Sodium Fluorescein), LDL-uptake and tube formation. hiPSC-BMEC were then combined with hiPSC-MC and hiPSC-astrocytes into a Transwell® co-culture model. WT hiPSC-derived BMEC exhibit high TEER of …

    cambridge Repository record

  8. Brain microvascular endothelial cell dysfunction in schizophrenia: a preliminary report

    Pong, Sovannarath2020

    … trans-endothelial electrical resistance (TEER) and efflux transporters activity of ABCB1 and ABCC1. We observed evidence of poor cellular adhesion and disrupted tight junctions in a subset of SZ hiPSC-derived BMECs, where approximately 70% of them demonstrated extensive BBB disruption …

    bu Repository record

  9. Investigating the impact of e-cigarettes on lung cells: a combined in vitro and computational study

    Aghababaie, MarziehResearchSpace@Auckland2025

    … via transepithelial electrical resistance (TEER), lactate dehydrogenase (LDH) release, IL-8 secretion, and gene expression. Nicotine salt and flavoured aerosols significantly reduced TEER, increased LDH and IL-8 levels, and downregulated OCLN, TJP1, SCNN1A, ATP1A1, AQP3, and CHRNA5, …

    auckland-ms Repository record

  10. The effects of ethanol and aspalathus linearis on immortalized mouse brain endothelial cells (bEnd5)

    Thomas, Kelly AngeliqueUniversity of the Western Cape2015

    … and HPRT. Transepithelial electrical resistance (TEER) was measured using the Ohm Millicell-electrical resistance system, while bEnd5 monolayer morphology was analysed using the Zeiss scanning electron microscope. Both concentrations of EtOH led to an overall decrease in cell viability, and a …

    western-cape Repository record

  11. Maternal stress signature and infant neurodevelopment: determining the beneficial effects of human milk oligosaccharides - an in vitro study

    Egan, AislingUniversity College Cork2024

    … using trans-epithelial electrical resistance (TEER) measurements. TNF- had no impact on TEER values, while 3’-SL appeared to increase barrier integrity in the TNF- treated barrier. Both high and low biologically stressed maternal serum treatment caused an increase in TEER values which 2’-FL …

    cork Repository record

  12. Generation and Characterization of Human Blood-Brain Barrier Models for Investigating Neuropsychiatric Disorders and Tumor Metastasis

    Li, Yunfei2024

    … the trans-endothelial electrical resistance (TEER) decreases to ~62% of the control values. Correspondingly, tight junction proteins and the endothelial glycocalyx that determine the integrity of the BBB are significantly disrupted. It was also found that CRKL, a gene within the 22q11.2 DS …

    cuny Repository record

  13. INVESTING THE ROLES OF E26 TRANSFORMATION-SPECIFIC HOMOLOGOUS FACTOR IN CYSTIC FIBROSIS LUNG DISEASE

    Pinte, LaetitiaCambridge university2023

    … (trans-epithelial electrical resistance (TEER), cilia motility, and cell migration) and functions known to be faulty in CFLD (CFTR function, survival to infection, and response to hypoxia). EHF-/- clones had significantly increased TEER values and forskolin-induced swelling while reducing …

    cambridge Repository record

  14. An Investigation of The Use of Dendrimer-Based Carrier to Cross Cellular Barrier

    Teow, Hueyminn (Stephanie)University of Central Lancashire2011

    … the transendothelial electrical resistance (TEER) across the cell monolayers. Successfully cultured cell monolayers that achieved TEER values of higher than 200 Ω.cm2 were used for permeability studies. Elevation of TEER was observed when PBEC monolayers were cultured in the serum-free medium …

    cent-lancashire Repository record

  15. Congreve's Love for Love: Valentine's voices

    Teer, BarbaraTexas Woman's University1966

    twu Repository record

  16. Exposure of 3D organotypic vaginal tissues to semen induces expression of the chemokine MCP-1, but does not alter tissue integrity

    Singh, Subha2018

    … and transepithelial electrical resistance (TEER) assessments. We used three multilayered differentiated EpiVaginal™ models: VEC-FT, which contained both epithelium and fibroblast layers; VEC-PT, which is comprised of differentiated epithelium only, and VLC, which has a normal epithelium in …

    bu Repository record

  17. The role of the gut microbiota in the function and integrity of brain barriers

    Knox, Emily G.University College Cork2023

    … by trans-endothelial electrical resistance (TEER). While we do not yet understand the dynamics of the BBB following acute stress, we know that microbial metabolites can interact with BBB function, so we next assessed the potential for acute-stress induced metabolites to regulate BBB integrity …

    cork Repository record

  18. Development of high performance tribological coatings for application onto hip joint prostheses

    Knox, PaulUniversity of Wolverhampton2010

    … an amorphous carbon coating developed by Teer Coatings Ltd. was modified and deposited onto CoCr and WHMWPE substrates in order to improve the wear properties. It was identified that depositing a hard coating onto soft substrate would cause high stresses and lead to coating delamination. …

    wlv Repository record

  19. hiPSC-Derived Cerebral Small Vessel Disease Models

    Al-Thani, MahaUniversity of Cambridge2023

    … Cells (iBMECs), which resulted in decreased TEER levels and increased permeability. They also induced apoptosis, migration defects, and transcriptome changes in hiPSCs-derived Mural Cells (iMCs). A co-culture system made of iBMECs and iMCs revealed that iMCs exert a detrimental paracrine …

    cambridge Repository record

  20. In Vitro Modeling of the Blood–Retinal Barrier: Investigating the Role of Pericyte-Like Adipose-Derived Mesenchymal Stem Cells and the Application of an iBRB on-a-Chip System [Modello in vitro di barriera emato-retinica umana: effetti delle cellule staminali mesenchimali adipose differenziate verso un fenotipo pericitico e applicazione di un sistema iBRB on-a-chip]

    AGAFONOVA, ALEKSANDRAUniversità degli studi di Catania2026

    … l’integrità di barriera mantenendo i valori di TEER e l’espressione delle proteine giunzionali VE-caderina e ZO-1. Inoltre, hanno attenuato l’espressione di mediatori pro-infiammatori e pro-angiogenici (TNF-α, IL-1β, VEGF, MMP-9) e ridotto l’attivazione dell’asse infiammatorio …

    catania Repository record

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