Global ETD Search
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Showing 1 to 1 of 1 for “"TDP-43, amyotrophic lateral sclerosis, frontotemporal dementia"”.
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Characterization of Codon Optimized Wild Type TDP-43 Mediated Neurodegeneration in a Drosophila Model for ALS.
TAR DNA Binding Protein-43 (TDP-43) is known to mediate neurodegeneration associated with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration-ubiquitin (FTLD-U). The exact mechanism by which TDP-43 exerts toxicity in patient brains remains unclear. In a Drosophila model, we …