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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 21 for “"TCSPC"”.
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RO-Based TDC Design with Configurable Resolution and Power for SPAD-Based TCSPC LiDAR Applications
… TDCs in time-correlated single-photon counting (TCSPC) applications are their CR, area, and power consumption. TDCs formed by ring oscillators (ROs) are arrayable, scalable, and low power, making them suitable for SPAD-based TCSPC 3D sensing systems. The jitter of RO-based TDCs is studied as a …
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Design and implementation of high linearity FPGA-TDCs and an integrated large scale TCSPC system for time-resolved applications
The time-correlated single-photon counting (TCSPC) technology is a vital, advanced measurement and analytical tool for time-resolved biomedical, physics research and many industry areas because of its high temporal resolution and sensitivity. Analogue-based conventional TCSPC systems have been …
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Long-range depth profiling based on time-correlated single-photon counting
… In time-correlated single-photon counting (TCSPC), every detection event is treated as an independent measurement of time. The build-up of photon statistics over many measurement cycles allows for time-of-flight measurements with a precision that can be superior to the system’s single-shot …
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High-speed electrochemistry using ultramicroelectrodes
… using time correlated single photon counting (TCSPC). Computer processing of the light intensity data can convert this data back to current. The technique is capable of measurements on nanosecond time scales, but TCSPC requires tens or hundreds of millions of experiments to obtain a complete …
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Konzeption und Umsetzung neuer Technologien zur biaxialen Winkelmessung und elektrooptischen Pseudostreckenmessung
… zur Formung des transversalen Strahlprofils, das TCSPC-System und die zur Auswertung und Kalibrierung notwendigen Algorithmen, wie z.B. die Autokollimation eines Lasers. ("Veröffentlicht von der Deutschen Geodätischen Kommission Reihe C (Dissertationen) unter der Nummer C 614 (München 2008; …
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LINEAR AND NONLINEAR FLUORESCENCE LIFETIME IMAGING FOR BIOSENSING APPLICATIONS
… Using linear or nonlinear excitation source, TCSPC-FLIM enabled real time monitoring of cellular metabolite profiles, as well as longitudinal observation of post-translational enzyme activity such as kinase phosphorylation and acetyltransferase acetylation. This technique will not only provide …
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Novel Iridium (III) complexes for photocatalytic H2 generation from H2O using sunlight
… Time Corelated Single Photon Counting (TCSPC), Laser Flash Photolysis and Gas Chromatography (GC) are briefly described in this chapter. Chapter 3 deals with the synthesis of iridium polypyridyl complexes with various cyclometallating ligands used for intermolecular and intramolecular …
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Investigation of biopolymer properties with combined fluorescence correlation spectroscopic and computational methods
… zeitkorrelierter Einzelphotonenregistrierung (TCSPC) und Fluoreszenzkorrelationsspektroskopie (FCS) von mit Fluoreszenzfarbstoffen markierten Polyprolinderivaten, F-(Pro)N-Trp (mit N = 2 - 10 und F = MR113, MR121, R6G), legen nahe, dass Sub-Populationen der Polyproline mit verringertem …
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Strategies towards high performance (high-resolution/linearity) time-to-digital converters on field-programmable gate arrays
Time-correlated single-photon counting (TCSPC) technology has become popular in scientific research and industrial applications, such as high-energy physics, bio-sensing, non-invasion health monitoring, and 3D imaging. Because of the increasing demand for high-precision time measurements, …
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Development of advanced 3D tissue models and O2 imaging methodologies
… seeding with both PC12 and HCT116 cells. Using TCSPC and PLIM multiplexed with fluorescent markers and fluorescent staining we could non-invasively correlate lifetime values with toxicity and drug stimulation. Several novel O2 and temperature-sensitive nanoparticle probes were evaluated. These …
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New photonic imaging systems for biomedical applications
… depth, accuracy, and general usability. TCSPC with raster scanning technique is frequently used in PLIM, but it is slow as it requires long pixel dwell times to measure long-lived phosphorescence. Other commonly used techniques include gated CCD and CMOS cameras, which lack single photon …
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Using the Marcus Inverted Region and Artificial Cofactors to Create a Charge Separated State in <i>De Novo</i> Designed Proteins
… quenching for investigating the rate of ET, TCSPC for fluorescence lifetime and transient absorption measurements at the picosecond timescale. v Protein constructs with viologens had their redox potentials determined through Dutton solution potentiometry and it was found that covalent …
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New approaches for optical and microoptical diagnostics in IC engines
… work, tracer-LIF lifetimes were measured via TCSPC (time-correlated single-photon counting) with unprecedented time resolution. The measured bi-exponential decay for toluene LIF could validate the prevailing model. Before the microoptical systems were finished, two experiments in optical …
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Light scattering: from ensembles to single particles
Light scattering enables the interrogation of nanoscale systems with minimal perturbation to their dynamics. However, this advantage of optical techniques is partially offset by requiring complex inference procedures to accurately estimate physical quantities of interest from features extracted by …
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Design and Synthesis of Photoactive Metal-Organic Frameworks for Photon Upconversion and Energy Transfer Studies
… and time-correlated single photon counting (TCSPC) spectroscopy and are compared to those of the corresponding ligand in solution. Both the unique fluorescent properties of the ligand as well as individual framework structure, result in distinctive luminescent behavior and dictate the extent …
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Development of new photoluminescent sensing materials, systems and applications for cell analysis
… Eclipse, and confocal laser-scanning FLIM/PLIM-TCSPC microscope. The merits and limitations of each platform, including instrumental factors, analytical performance, lifetime calculation methods, potential sources of error were assessed. The third experimental section presents a new …
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Multiphotonenmikroskopische Untersuchungen und Kategorisierung von humanem Knorpelgewebe sowie 2-Photonen-Mikroendoskopie
… Fluoreszenzlebensdauer. Mit dem installierten TCSPC-System ist es möglich, Fluoreszenz-Lebenszeit-Imaging durchzuführen. Die beiden Hauptanwendungen des Systems waren die Bewertung von humanem Knorpelgewebe sowie die Untersuchung von Proteindynamiken in Pflanzenzellen. Humanes Knorpelgewebe …
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Luminescent Properties of Anthracene-based Metal-Organic Frameworks
… and time-correlated single photon counting (TCSPC) emission lifetime spectroscopy. The addition of carboxylic acid functional groups on the anthracene ring alters photophysical properties to varying degrees depending on the location and protonation state. Density functional theory (DFT) …
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Synthesis and Characterization of pure-phase Zr-MOFs Based on meso-Tetra(4-carboxyphenyl)porphine
… time-correlated single photon counting (TCSPC) spectroscopy and nanosecond transient absorption spectroscopy. The effects of the surrounding media and temperature on the excited-state properties of PCN-223(fb) were explored to understand the mechanistic aspects of energy transfer. …
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Design, synthesis and characterization of photocage molecules for light-activated release: Applications in polymer chemistry and phototherapeutics
… by time correlated single photon counting (TCSPC) experiments, even though no correlation was observed between the amount of deuterium incorporation and the increase in fluorescent lifetime.
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