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Showing 1 to 1 of 1 for “"TC21"”.

  1. The role and function of the Ras-related protein TC21 in Neurofibromatosis type 1

    … proteins H-Ras, N-Ras, K-Ras, M-Ras, R-Ras, and TC21. Missense mutations in the GAP related domain of neurofibromin cause NF1 disease, indicating that increased Ras activity is likely critical for disease pathogenesis. Loss of NF1 in Schwann cells causes formation of benign tumors known as …

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