Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"TC-NER"”.
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Étude de la réparation des lésions induites par les UVs dans les extrémités chromosomiques de la levure Saccharomyces cerevisiae
… de réparation par excision de nucléotides (NER pour « Nucleotide Excision Repair ») permet d’éliminer les photoproduits. La NER est un mécanisme très bien conservé de la levure à l’humain. Elle est divisée en deux sous voies : une réparation globale du génome (GG-NER) et une réparation …
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Understanding the biological processes underpinning neurodegeneration in Xeroderma Pigmentosum
… genetic disorder of nucleotide excision repair (NER). XP is classified into eight complementation groups, XP-A to XP-G and V, depending on the protein component of the NER pathway that is defective. NER is split into two branches. Transcription coupled repair (TC-NER), which rapidly repairs DNA …
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Functional DNA repair capacity assays : a focus on base excision repair
… can lead to cancer, immunodeficiency and degenerative disease. Quantitating and understanding an individual's DNA repair capacity may enable us to predict and prevent disease in a personalized manner. Base Excision Repair (BER) is known for the recognition and repair of endogenous and …
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Mechanism of Incorporation and Repair of Uracil At Highly Transcribed Genes In Saccharomyces Cerevisiae
… in DNA and the associated physical obstacles generated by the transcription machinery. However, such explanation does not directly account for the unique types of mutations originating from the non-canonical residues such as uracil, which are also elevated at highly transcribed regions. …