Global ETD Search
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Showing 1 to 4 of 4 for “"TBP-like protein"”.
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Transcriptional regulation in Plasmodium falciparum: characterisation of TBP-like protein
… is hitherto poorly understood. The TATA-binding protein (TBP) is a universal transcription factor required for transcription by RNA polymerase I, II and III. Multiple gene duplication events throughout eukaryotic evolution have resulted in many eukaryotes harbouring more than one TBP family …
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Expression and initial characterisation of the Plasmodium falciparum general transcription factors TFIIB and TLP
… because very little is known about both the key protein factors and DNA elements which guide the assembly of RNAPII components into the transcription initiation complex. Bioinformatics studies have shown that there is very little amino acid sequence conservation between human and Plasmodium …
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Functional divergence of the RNA polymerase II transcription machinery in Plasmodium falciparum
… falciparum general transcription factors - two TBP family proteins designated the TATA-binding protein (TBP) and TBP like protein (TLP), and the P. falciparum orthologue of general transcription factor IIB (TFIIB). Through the biochemical characterisation of protein-DNA interactions, …
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Functional Characterization of Plasmodium falciparum TATA-box binding-like Protein (PfTLP)
… Milton, 2017), including a TATA box-binding-like protein, PfTLP. Bioinformatic analysis suggested that PfTLP is a TRF2-type TBP-like protein. However, PfTLP differs in several aspects from previously characterized TRF2-type proteins. These differences are thought to be Plasmodium specific …