Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"TAX1BP1"”.
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Crystallographic and Modeling Studies Suggest that the SKICH Domains from Different Protein Families Share a Common Ig-like Fold but harbor substantial Structural Variations
TAX1BP1 is a pleiotropic multi-domain protein involved in many important biological processes such as signal transduction, cell growth and apoptosis, transcriptional coactivation, membrane trafficking, neurotransmission and autophagy. The N-terminus of TAX1BP1 contains a SKICH domain implicated in …
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Decoding Lysine-11 Signals in Ubiquitination
… the mitophagy ubiquitin receptors, MyosinVI and TAX1BP1. Heterotypic K11/K48 linkages not only bound the proteasome but also stimulated degradation of the cell cycle substrate, cyclin B1. To further explore the functions of K11-chains I focused on the hypoxia inducible transcription factor (HIF) …
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Targeting Innate Immune Memory to Alleviate Monocyte Exhaustion and Chronic Inflammation
… production of compensatory immune suppressors TAX1BP1 and PLAC8. The whole genome methylation analyses further demonstrate that M-MA effectively erases the methylation memory of exhausted monocytes, with confirmed restoration of Plac8 methylation by M-MA. In the second project, we showed that …