Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"TATA-box binding protein (TBP)"”.
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Function of core promoters in differential gene regulation during embryogenesis
… requirement for the general transcription factor TATA-box binding protein (TBP), a diverse set of promoters was tested for their TBP dependence. This analysis revealed a differential requirement of TBP for promoter activity. To further explore the roles of core promoters the ability of various …
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Expression and initial characterisation of the Plasmodium falciparum general transcription factors TFIIB and TLP
… because very little is known about both the key protein factors and DNA elements which guide the assembly of RNAPII components into the transcription initiation complex. Bioinformatics studies have shown that there is very little amino acid sequence conservation between human and Plasmodium …
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Functional Characterization of Plasmodium falciparum TATA-box binding-like Protein (PfTLP)
… factors (Bing, 2014; Milton, 2017), including a TATA box-binding-like protein, PfTLP. Bioinformatic analysis suggested that PfTLP is a TRF2-type TBP-like protein. However, PfTLP differs in several aspects from previously characterized TRF2-type proteins. These differences are thought to be …
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Eukaryotic Transcriptional Activation Mechanism: Protein-Protein Interactions
… in eukaryotes: activators target TFIID (TBP)-TFIIB promoter complex formation in the preinitiation complex assembly process by inducing (or stabilizing) qualitative or quantitative alterations within TFIID (TBP)-TFIIB-promoter complexes that consequently enhance recruitment of downstream …
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A Molecular Characterization of Human General Transcription Factor IID
… of organisms, including human, encoding a protein that may substitute native TFIID fractions in DNA binding and in vitro basal transcription assays. Sequence comparisons identify important structural motifs in the protein. Further functional analyses lead to the realization that this …