Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 42 for “"TATA box"”.
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Functional Characterization of Plasmodium falciparum TATA-box binding-like Protein (PfTLP)
… factors (Bing, 2014; Milton, 2017), including a TATA box-binding-like protein, PfTLP. Bioinformatic analysis suggested that PfTLP is a TRF2-type TBP-like protein. However, PfTLP differs in several aspects from previously characterized TRF2-type proteins. These differences are thought to be …
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Statistical pattern recognition based on LVQ artificial neural networks : application to TATA box motif
Dissertation submitted in compliance with the requirements for Masters Degree in Technology in the Department of Electrical Engineering (Light Current, Technikon Natal, Durban, South Africa, 2000.
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Die Regulation der humanen H3-Histongene
… untersucht. Im H3/m-Promotor wurden die TATA-Box, die proximale und distale CCAAT-Box und eine ATF-Box identifiziert. Im H3/k-Promotor wurden als wesentliche funktionelle Elemente die TATA-Box und die proximale und distale CCAAT-Box identifiziert. Der funktionelle Grundaufbau der …
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Promoters and Heterogeneous 5' Termini of the Messenger RNAs of Adenovirus 2
… form of region IIa mRNA have clearly defined TATA box homologies. With early region IIa and IVa2, this homology is absent. For most messengers, the mRNA terminus is microheterogeneous, and encoded within a 2-7 base cap site region located approximately 30 nucleotides downstream from the TATA …
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A Molecular Characterization of Human General Transcription Factor IID
… lead to the realization that this protein is the TATA box binding subunit (TBP) of a multi-protein TFIID complex whose other constituents are required for activator-responsive in vitro transcription and are responsible for TFIID's characteristic DNA interactions around the initiation region. A …
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Studies on the Activity of the Long Terminal Repeat of Rous Sarcoma Virus in Animal Cells and in Yeast
… transcription was mostly dependent on two CCAAT boxes in the LTR, though other upstream sequences may play a secondary role. Serum caused the rapid appearance of a nuclear protein that binds to the two CCAAT boxes. This serum-induced CCAAT factor was also bound by CCAAT sequences from other …
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Application of Single-Molecule Analytical Methods for the Characterization of Multimeric Genetic Elements in Yarrowia lipolytica DSM 3286
… sequence and to discover novel lncRNAs. The TATA box and Inr consensus sequences of Y. lipolytica DSM 3286 were determined, and analysis of the distance between the TATA box location and the TSS revealed a strong correlation between positional conservation and high gene expression levels or …
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Transcription regulation in Plasmodium falciparum : functional characterisation of general transcription factor IIB
… bias toward A/T in the Plasmodium genome, TATA-box and other core promoter elements that direct transcription initiation, cannot be determined with confidence in bioinformatics studies. Functional characterisation of the key protein factors involved in transcription initiation is a first …
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The Role of DNA Binding in Transcription Activation by Estrogen Receptor
… the estrogen response element (ERE) linked to a TATA box, it exhibited a 10 fold increase in hormone-independent constitutive transcription activity compared to that of the wild-type XER. The hormone binding properties and protein expression levels of both the wild-type XER and the XER/2AH mutant …
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Structure and expression of a U1 snRNA gene from Arabidopsis thaliana
… described for other plant snRNAs: the CAAT box, $-$78 sequence, TATA box and 3' box. The U1a promoter also contains the octamer motif, a sequence element commonly found in vertebrate snRNA genes. In addition, U1a contains five sequence motifs repeated numerous times in the promoter. Three of …
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Zur Bedeutung der polyTC-Motive in den Promotoren und 5‘-UTR-Bereichen konstitutiv exprimierter Pflanzengene
… im Promotor und der 5’UTR je eine Polypyrimidinbox. Solche Motive aus sich häufenden TC-Alternierungen sind in pflanzlichen Promotoren und 5’UTRs ein häufig auftretendes Motiv mit bislang weitgehend ungeklärter Funktion. Am Beispiel des Promotors Y11037 des konstitutiv exprimierten V-ATPase c1 …
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Isolation and sequencing of a genomic clone of ESI28 : an early salt-stress induced gene of the salt-tolerant wild wheatgrass Lophopyrum elongatum
… sequence contains a putative TATA box and abscisic acid (ABA) response element (ABRE). The genomic clone contains a long open reading frame (ORF) which encodes a polypeptide of 143 amino acids with a predicted molecular mass of 15.95 kDa. The protein has two conserved domains …
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Molekulare Charakterisierung des Retrotransposons Ylt1 der Hefe Yarrowia lipolytica
… Die LTR Sequenzen enthalten nicht nur TATA-Box, sondern auch ein mögliches Terminations-Signal der Transkription (TAGT) sowie ein Polyadenylierungssignal (AATAAA). Eine Primer Bindungsstelle und ein Polypurin-Bereich sind ebenfalls innerhalb der Ylt1 Sequenz enthalten. Dieses …
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Function of core promoters in differential gene regulation during embryogenesis
… requirement for the general transcription factor TATA-box binding protein (TBP), a diverse set of promoters was tested for their TBP dependence. This analysis revealed a differential requirement of TBP for promoter activity. To further explore the roles of core promoters the ability of various …
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Charakterisierung des negativen Cofaktors 2 der RNA-Polymerase II in vivo und in vitro
… Transkriptionsrepressor, welcher stabil an das TATA-Box bindende Protein (TBP) bindet. Die spezifische Bindung von NC2 an TBP inhibiert die weitere Anlagerung der generellen Transkriptionsfaktoren TFIIA und TFIIB und führt dadurch zur Unterbrechung der Bildung des Initiationskomplexes. NC2 …
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Gene Expression in Archaea: Studies of Transcriptional Promoters, Messenger RNA Processing, and Five Prime Untranslated Regions in Methanocaldococcus Jannashchii
… eukaryotic RNA polymerase II promoters, with a TATA box and a transcription factor B recognition element being the core promoter elements. Protein-coding gene promoters bind transcription factors less tightly than do most tRNA gene promoters. Results show a correlation between promoter sequence …
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Cloning, sequencing and functional analysis of the chicken tyrosine gene promoter
… region and an associated SP1-binding site, the M-box and an upstream enhancer element, TDE. In addition, other potential transcription factor binding motifs were identified, including an AP-1-binding site, a UV-responsive element and glucocorticoid-responsive elements. Although several TATA box …
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DNA sequences required for efficient transcription of the estrogen regulated Xenopus laevis vitellogenin promoter
… has been characterized. Mutation of the CAAT box or deletion of a conserved nematode box or the entire region between -301 and -121 had no significant effect on vitellogenin promoter activity. An eight base DNA element with weak sequence homology to the NF1 element is essential for efficient …
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Isolation, characterization and expression of a peach nuclear gene encoding a light-harvesting chlorophyll a/b-binding polypeptide of photosystem II
… start site and 44 bp downstream from a putative TATA box. Multiple polyadenylation sites are present in the 3$\sp\prime$ flanking region. The seasonal expression of Lhcb1*Pp1 was determined by Northern blot and S1 nuclease protection analyses. Both analyses indicate that the relative level of …
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Perinatal Nicotine Exposure and Programming of HIE Sensitive Phenotype in Neonatal Rat Brains
… methylation status of a single CpG adjacent to TATA-box at AT2R promoter, inhibiting TBP and recruiting MeCP2 binding, repressing AT2R gene expression, contributing to the enhanced vulnerability to HIE brain injury in male rat pups. All of pathological effects are reversed by administration of …
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