Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"TAF15"”.
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Molecular analysis of the FET family fusion oncoprotein FUS-DDIT3
… cancers. The FET family genes (FUS, EWSR1 and TAF15) occur in translocations with genes encoding various transcription factors in sarcomas and leukemias. The resultant fusion genes encode chimeric protein products containing the N-terminal domain (NTD) of a FET family protein juxtaposed to the …
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Identifying CDK8/19 as a Novel Regulator of EWS-FLI1 Function in Ewing Sarcoma
… from an RNA binding protein (EWSR1, FUS, or TAF15) with the DNA binding domain of an ETS transcription factor. The translocation EWS-FLI1 accounts for 90% of Ewing sarcoma tumors and a large body of evidence suggests that EWS-FLI1, acting as an oncogenic transcription factor, is the main …