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Showing 1 to 2 of 2 for “"TAAP"”.
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Developing 1,2,3,4-tetrahydro-5H-aryl[1,4]diazepin-5-ones and Related Scaffolds as Poly-(ADP-ribosyl) Polymerase (PARP) Inhibitors and Exploring Their Targeted Polypharmacology with Kinases
… the development of the tetrahydro-arylazepinone (TAAP) scaffold as a potential dual PARP1/CDK1 inhibitor. We screened a handful of TAAP analogs against PARP1 in a cell-free assay that identified the low micromolar PARP1 inhibitor 1,2,3,4-tetrahydro-5H-benzo[e][1,4]-diazepin-5-one (TBAP), which …
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A Comparison of the Similarities and Differences between Traditionally and Alternatively Prepared First Year Secondary Teachers in a Large Middle Georgia School District
This mixed-method study examined mentor teachers' perception of the extent to which first-year teachers exhibit the knowledge, skills and dispositions of accomplished teachers during the 2008-2009 school year in a large school system in central Georgia. The data, collected from an online survey of …