Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"T36M"”.
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Investigating WNT signalling in the lung
… Both lung tissue samples from 9-month-old Pkhd1T36M/T36M mice and A549 cells were used in this study. Key proteins from both canonical and non-canonical Wnt pathways were quantified by Western blotting to determine the primary intercellular Wnt signalling pathway associated with lung hypoplasia …
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An in vivo study of novel genetic modifiers in autosomal recessive polycystic kidney disease (ARPKD)
Autosomal Recessive Polycystic Kidney Disease (ARPKD) is a rare genetic disorder that manifests with bilaterally enlarged, cystic kidneys, hepatic fibrosis and pulmonary hypoplasia, with death reported in around 30 – 50% of affected neonates. Mutations in PKHD1 and DZIP1L have been identified as …