Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"T1R3"”.
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Studies on Cellular Nutrient Responses and Protein Degradation
… G protein coupled receptor (GPCR) T1R1-T1R3 can act as an extracellular sensor for amino acids, promoting mTOR activity while repressing autophagy in cells. Quantitative PCR analysis revealed that T1R3 depletion increases mRNA expression of amino acid transporters as a compensatory …
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Dietary carbohydrates influence the structure and function of the intestinal alpha-glucosidases
… on the sweet taste receptor subunits (T1R2 and T1R3) by qRT-PCR showed that the expression of T1R2 and T1R3 increased in presence of maltose compared to glucose. It appeared also that maltooligosaccharides may signal other events in small intestine enterocytes. Culture-related conditions (e.g. …
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The Physiological Role of Serotonergic Transmission in Adult Rat Taste Buds
… markers, including taste receptor molecules T1R3 and T2R9, involved in detecting bitter, sweet, and umami tastes. 5-HT1A did not co-express with type III TRC-specific markers PKD2L1 and NCAM, confirming the paracrine nature of 5-HT signaling in the taste bud. To examine the functional role of …
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Neuroanatomical Maps and Taste Reactivity to Sweet, Umami, and Bitter Taste in the PBN of C57BL/6J Mice
… common G-protein-coupled taste receptor subunit, T1R3, that responds in combination with either T1R1 to transduce umami stimuli or T1R2 to transduce sweet stimuli. Aside from sharing a common taste receptor, previous studies using pharmacological manipulations, electrophysiology, conditioned taste …
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Conformational engineering of human chemokine receptors and HIV-1 Env using deep mutational scanning
Experimental analysis of protein mutations is classically a ‘small data’ problem. A limited number of mutants are made at sites of suspected importance, and the activity of each variant is individually tested. However, by combining directed evolution and deep sequencing with site- saturation …