Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 44 for “"T1DM"”.
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Increased Lipid Metabolism in Response to Repetitive Aerobic Exercise During Proestrus in Type 1 Diabetes Mellitus Rats
… of aerobic exercise, type I diabetes mellitus (T1DM) female rats demonstrate greater post-exercise blood glucose (BG) recovery during proestrus than T1DM males. Fuel selection differences may explain sex-related differences in the blunted counterregulatory responses to subsequent exercise and …
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A cost-utility and budget impact analysis of long-acting insulin analogues, (determir, glargine and degludec) for the treatment of adults with T1DM in South Africa
Background: Type 1 Diabetes Mellitus (T1DM) is a life-threatening condition that is managed with administered insulin. Intermediate- to long-acting insulin represents the basal insulin constituent of the total insulin used in treating T1DM and has received much research and development over the …
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A Qualitative Exploration of Self-Care Behaviors for Disease and Symptom Management Among College Students with Type 1 Diabetes Mellitus
… been diagnosed with Type 1 Diabetes Mellitus (T1DM), the effects of inadequate management can lead to hospitalizations, additional development of chronic health conditions, and early mortality. Therefore, T1DM self-care behaviors (e.g., administering insulin, monitoring blood glucose) must be …
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Poor glycaemic control in adolescents with type 1 diabetes
Many adolescents with type 1 diabetes (T1DM) have suboptimal glycaemic control, increasing the risk of diabetic complications. This thesis explores some of the causes, consequences and therapeutic options for adolescents with T1DM and poor glycaemic control. Insulin resistance occurs in T1DM and …
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Naujai diagnozuotas cukrinis diabetas po COVID-19 infekcijos /
… and the onset of type 1 diabetes mellitus (T1DM)s. 2. To compare the frequency of new onset T1DM between patients who were infected with COVID-19 and those who were not. 3. To evaluate the frequency and prevalence of new onset T1DM cases during and after the COVID-19 pandemic, compared to …
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Characterizing neurodegeneration, neuroinflammation and immunological status through multimodal strategies in type 1 diabetes mellitus and relapsing-remitting multiple sclerosis
Type 1 diabetes mellitus (T1DM) and Multiple sclerosis (MS) are chronic organ-specific diseases caused by immune system dysfunction. The study of T1DM and MS has gained increasing attention because of their high prevalence, progressive nature, impact on patients' daily lives, the lifelong …
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Implementing an exercise intervention on young adults at university with type 1 diabetes.
… components of type 2 diabetes, type 1 diabetes (T1DM) is recognised as by insulin deficiencies because of the autoimmune driven destruction of pancreatic β cells (Sigal et al., 2013). Globally, T1DM affects over 1 million young people aged between the ages of 0 to 20 years and this number is on …
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Evaluation of Metabolic Risk in Relation to Visceral Adiposity and Physical Activity in Patients with Long-Standing Type 1 Diabetes // Оценка на метаболитния риск във връзка с висцералната мастна маса и физическата активност при пациенти със захарен диабет тип 1 с голяма давност
… with long-standing type 1 diabetes mellitus (T1DM) with childhood onset. A prospective case–control study was conducted, including 124 patients with T1DM (disease duration >15 years) and 59 healthy controls matched for age, sex, and BMI. Advanced approaches were applied to determine VAT (DXA, …
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The impacts of a health education programme on primary school teachers' knowledge and attitudes towards type 1 diabetes mellitus in children in Saudi Arabia
IntroductionThe incidence of T1DM in the Kingdom of Saudi Arabia (KSA) is particularly high at 36.99 per 100,000. The number of newly diagnosed cases in children (0-14 years) is estimated at 10,700 per year, constituting a major public health problem. Schools are important for secondary prevention, …
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Youth With Type 1 Diabetes Mellitus: An Examination Of Adolescents’ Illness Perceptions And Associated Impact On Health-Related Quality Of Life
… surveys were administered to adolescents with T1DM by a member of the research team. Structural equation modeling was utilized to test the proposed study model and examine the relationships hypothesized therein. Results: The final model fit the data well and explained 49.1%, 40.4%, 59.1%, and …
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Experiences of caregivers regarding homecare of children with type1-diabetes mellitus within Vhembe District of Limpopo Province, South Africa
Worldwide, Type-1 diabetes mellitus (T1DM) was a devastating condition for both the diagnosed children and caregivers taking care of them. These challenges were drastically affecting caregivers in rendering the required homecare service for their patients. Vhembe District had been experiencing a …
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Feasibility and acceptability of a mother-daughter intervention to address disordered eating behavior among adolescent girls living with type 1 diabetes mellitus
… Adolescent females with Type-1diabetes (T1DM) are at higher risk for DEB and have a two-fold higher incidence of disordered eating behavior (DEB) than their non-diabetic counterparts. Individuals with T1DM have the unique ability to omit insulin as a weight reduction strategy. DEB in …
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Functional, Structural and Molecular Alterations in the Heart and Kidney During Diabetes Mellitus
… and neuropathy that are common in type 1 DM (T1DM) and type 2 DM (T2DM). Epidemiological studies have demonstrated a role of hyperglycaemia (HG) in eliciting adverse cardiac and renal outcomes including heart failure (HF), diastolic and renal dysfunction. This study investigated the effect of …
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Pharmacological modulation of insulin resistance - benefits and harms
… insulin resistance in type 1 diabetes (T1DM). This thesis examined: (i) cardiovascular, renal and metabolic differences between individuals with T2DM ‘tolerant’ or ‘intolerant’ of TZDs; (ii) risk factors for TZD-associated oedema in T2DM; and (iii) the potential for metformin as adjunct …
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Diabetes in children: impact of an innovative pharmaceutical care programme and links with concurrent illnesses
… included 212 children ≥ 18 years of age with T1DM (Chapter 2). Those randomised to a pharmacist-managed clinic received education from a pharmacist on their condition, treatment and self-management in a structured fashion, while those in the control group received routine care. Both groups …
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Inflammasome upregulation and activation in photoreceptors of type 2 diabetes and N-methyl-N-nitrosourea models is attenuated by Wedelolactone
… it may differ between type 1 diabetes mellitus (T1DM) and T2DM has not yet been determined. There are several types of inflammasome but the so-called AIM2 inflammasome pathway may be the most important in this disease context, since it critically controls the production and maturation of …
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A 4-month randomized controlled clinical trial of adjuvant exenatide or pramlintide versus insulin alone in pediatric type 1 diabetes mellitus: Effect on glycemic control
… in pediatric Type 1 Diabetes Mellitus (T1DM). We present here the preliminary results (n=24) of a Phase III randomized clinical trial designed to compare the glycemic effects of using adjuvant Pramlintide or Exenatide versus insulin alone in pediatric T1DM. Sample size calculations …
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Improving Pediatric Type-1 Diabetes Mellitus Management in Rural Utah: A Case Study
… case study has a well-documented history of poor T1DM control. Her pediatric endocrinologist is located over 2 hours away from her home. Reported blood glucose levels average above 200 mg/dL, with a recent glycosylated hemoglobin (HbA1c) level of 10.3%. Previous blood glucose levels have reached …
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The effect of insulin treatment and exercise modality on skeletal muscle fiber size in streptozotocin-induced type 1 diabetic rats
Severe Type 1 Diabetes Mellitus (T1DM) is known to have several negative effects on skeletal muscle mass, a condition known as diabetic myopathy. One of these effects is the atrophy of the glycolytic muscle fibers. However, the role of intensity of insulin treatment and exercise modality in …
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An Exploration of Diabetes Self-Care Among Older Adolescents with Type 1 Diabetes: A Focus Group Study
<p>Background: Type 1 diabetes (T1DM) is a chronic illness that requires intensive treatment to improve glycemic control and limit the risk of diabetes-related complications. The management of T1DM is challenging for adolescents as the diabetes self-care activities invade all aspects of their life. …
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