Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 281 for “"T-lymphocytes"”.
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B and T Lymphocytes in Human Pregnancy
… this purported depression was due to fewer T-lymphocytes or a dysfunction of these cells. T cells were measured by the rosette technique using neuraminidase treated sheep red blood cells (SRBC). B cells were measured using a SRBC-hemolysin-guinea pig complement indicator system. The total …
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Telomere and Telomerase Dynamics in Human T Lymphocytes
Advanced cancer is characterized by a phenotype that permits cells to divide indefinitely while cellular aging is characterized by cells ceasing to divide. It is believed that senescence may have evolved as an anti-cancer protection mechanism in long-lived species such as humans. Therefore, cancer …
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Biological effects of trogocytosis on CD4+ T lymphocytes
<p>Antigen recognition by CD4+ T cells leads to large-scale spatial and temporal molecular redistributions, forming the immunological synapse. We have previously shown that upon dissociation, T cells capture large membrane fragments from antigen-presenting cells directly from the immunological …
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Biological effects of trogocytosis on CD4+ T lymphocytes
<p>Antigen recognition by CD4+ T cells leads to large-scale spatial and temporal molecular redistributions, forming the immunological synapse. We have previously shown that upon dissociation, T cells capture large membrane fragments from antigen-presenting cells directly from the immunological …
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Modulation of T Lymphocytes by Tumor-Released Survivin
… Of primary interest are tumor-infiltrating T lymphocytes, which have been shown to have a key role in modifying the dynamics of the tumor microenvironment to promote or prevent tumor growth. While there is much in vitro and in vivo evidence for a modification of the tumor infiltrating T cell …
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Generating memory cytotoxic T lymphocytes through repetitive peptide boosting
Cytotoxic T lymphocytes (CTLs) play a critical role in controlling intracellular pathogens and cancer cells, and induction of memory CTLs holds promise for developing effective vaccines against critical virus infections. However, generating memory CTLs remains a major challenge for conventional …
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Effector CD4⁺ T lymphocytes in the prodrome of polyarthritis
… days) or adoptive transfer of arthritogenic TD lymphocytes (4-6 days) suggests that progressive differentiation or selection of effector cells is required before disease can be expressed. This study has charted the emergence of activated and arthritogenic CD4⁺ T cells in the inguinal and …
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Role of CD4+CD25+ Regulatory T Lymphocytes in Experimental Toxoplasmosis
… investigate the role of CD4+CD25+ T regulatory lymphocytes in mice infected with <i>Toxoplasma gondii</i>. T regulatory (Treg) cells have been shown to play an important role in our immune system in controlling the activity of other T lymphocytes. These cells are differentiated from other T …
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APOBEC3 Transcriptional Regulation and HIV-1 Restriction in T Lymphocytes
… therapies. HIV-1 primarily infects CD4+ T lymphocytes, and to a lesser degree, macrophages, monocytes and dendritic cells. In the absence of therapeutic intervention, HIV-1 infection results in the gradual depletion of CD4+ T cells, leading to a severely compromised immune response and …
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Environmental signals that control T lymphocytes in the gastrointestinal tract
… influence of HIF-1α-ARNT complexes in mucosal lymphocytes has yet to be addressed. Here, we investigated the roles of AHR-ARNT and HIF-1α-ARNT signalling in lymphocyte maintenance at barrier surfaces. Firstly, we demonstrated that AHR-ARNT signalling can be detected in vivo at the intestinal …
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Protein complexes and microclusters. Regulation of signaling nodes in T lymphocytes
Contains fulltext : 141383.pdf (Publisher’s version ) (Open Access)
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