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Showing 1 to 1 of 1 for “"T-lineage commitment"”.
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Role of Notch Signaling and GATA-3 in Establishing T-lineage Commitment and Survival in Developing Thymocytes
… is required to commit progenitors to the T-lineage and acts in concert with many transcription factors such as GATA-3 to fully induce this fate choice while inhibiting the B-cell lineage. Although both Notch and GATA-3 are indispensible for thymocyte development, their precise roles in …