Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"T-cell receptor excision circle"”.
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Recent Thymic Emigrants and their Biomarkers
The main development of T cells takes place in the thymus. However, T cells that have just exited the thymus, called Recent Thymic Emigrants, are not yet fully matured and thus have different characteristics and functionalities than mature peripheral T cells. Several biomarkers exist for these …
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Development and Validation of Quantitative PCR Assays for DNA-Based Newborn Screening of 22q11.2 Deletion Syndrome, Spinal Muscular Atrophy, Severe Combined Immunodeficiency and Congenital Cytomegalovirus Infection
… and quantification of the SCID biomarker, T-cell receptor excision circles (TRECs) and CMV were all required for disease confirmation. SMA and 22q11.2 gene deletions were accurately detected using the OpenArray system, a first for the technology. The medium density deletion 22q11.2 multiplex …