Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"T-cell mediated rejection"”.
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Characterizing the Immunogenicity of Islet-like Cells derived from HLA-edited Human Pluripotent Stem Cells
… much hope for the therapeutic use of islet-like cells generated from human pluripotent stem cells, important challenges limit the clinical translation of this technology. In this thesis, I describe my efforts to address two of these challenges: the inability to control the composition of the …
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The spectrum of HIV-related kidney disease in South Africa
… we report a high cumulative incidence of rejection episodes, with 36% showing T-cell-mediated rejection or antibody-mediated rejection (ABMR). Non-rejection findings included fibrosis, pyelonephritis, and calcineurin toxicity. Features of HIVAN were identified in nine patients. ABMR …
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Renal allograft biopsies at Groote Schuur Hospital: a histopathologic descriptive study with molecular insights
… treatment for end-stage kidney disease. Immune-mediated rejection remains a barrier to success. It is diagnosed through the Banff classification, which incorporates histopathology and biomarkers (C4d/donor specific antibodies (DSA)). In resource-limited settings, DSA testing can be challenging, …