Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 1 of 1 for “"T cell, T cell receptor signaling, Library screening, PHA-767491, Cdc7, Cdk9"”.
-
IDENTIFICATION OF CDC7 AS A NEW REGULATOR OF T CELL ACTIVATION
In this thesis, a novel screening assay was designed to identify novel mediators of TCR signalling. A library of kinase inhibitors was screened for their effects on suppressing activation in several T cell populations. The screening assay was able to identify inhibitors of canonical kinases of TCR …