Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Systems and Integrative Engineering"”.
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Quantifying Parkinson's Disease Symptoms Using Mobile Devices
… of Parkinson’s Disease are largely qualitative and based on small sets of data obtained from occasional doctor-patient interactions. There is a clinical need to improve the techniques used for mitigating common Parkinson’s Disease symptoms. Available data sets for researching the disease are …
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Collective Behavior of Drosophila Melanogaster Neural Progenitor and Imaginal Disc Cells within Controlled Microenvironments
… cells to recapitulate developmental processes and initiate functional regeneration in different components of the eye. The developing visual system in Drosophila Melanogaster offers a model in which to analyze the associated processes in retinogenesis. The optic nerve is critical to vision and …
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Examining the Effects of transcranial Electrical Stimulation on Vigilance and Attention
… of human physiology, where oscillatory neural and physiological dynamics fluctuate between deep sleep and hyper alert states, over acute and diurnal cycles. Within the arousal spectrum, constructs like attention and vigilance aid in filtering and regulating ongoing exogenous sensory and …
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Neuron-Glial (NG) Interactions: A Microfluidic Examination of NG Emergent Responses for Repair
… is crucial to the development, plasticity, and repair of the nervous system (NS). While neurons are well known to conduct electrical impulses that transfer biological information and stimuli throughout the NS, our understanding of the roles of glia continues to evolve from when the cells …
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Development of Medical Device for Volume Status Assessment Using Peripheral Venous Pressure
The severe side effects of acute dehydration and blood loss may be prevented if assessed and treated quickly. As amplifier technology has improved, small peripheral venous pressure (PVP) signals collected using a transducer on an intravenous catheter can be analyzed to monitor patient volume …
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A Secure Behavior Modification Sensor System for Physical Activity Improvement
… large amounts of information about a person and their interaction within their home environment. However, what is missing is how to ensure the security of the collected data and its use to alter human behavior for positive benefit.</p> <p>In this research, exploration was conducted involving …
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Intensification of Gas Absorption in a Downward Flow Microbubble Bioreactor
… are of interest for value-upgrading of stranded or waste industrial gases, such as CO, CH<sub>4</sub>, or syngas. Process economics requires reduction of reactor cost and size while maintaining high production rate via rapid delivery of gas feedstock to the liquid phase which in turn …
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Design, Characterization and Application of a Multiple Input Stethoscope Apparatus
… implementation, characterization, calibration and possible applications of a multiple transducer stethoscope apparatus were investigated. The multi-transducer sensor array design consists of five standard stethoscope diaphragms mounted to a rigid frame for a-priori knowledge of their relative …
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A Microfluidic Tissue Array (µFTA) For Personalized Medicine using Tumor Biopsies
… as a complex disease with both genetic and epigenetic drivers that can vary from one individual to another. While very early research into cancer treated it as a clonal malfunction that could originate from as small as a single deregulated cell, the disease itself manifests itself with …
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Hypoxic Incubation Chamber
… paper describes the design, manufacturing, and testing of a novel controllable hypoxic incubator with fully functional oxygen gas control and temperature control in a humid environment. On the current market, a majority of the few hypoxic incubators use pre-mixed gas that does not offer …
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Optimizing Transcranial Focused Ultrasound: Calibration, Neuro Navigation, and BOLD fMRI Evidence of Neuromodulation
… thesis presents the development, calibration, and initial implementation of transcranial focused ultrasound (tFUS) for neuromodulation in a human study. The primary objectives were to design a system capable of delivering precise and safe ultrasound stimulation to targeted brain regions and to …
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Development of light actuated chemical delivery platform on a 2-D array of micropore structure
… information transfers within biological systems. Thus, the ability to mimic the natural chemical signal modulation would provide significant contributions to understand the functional signaling pathway of biological cells and develop new prosthetic devices for neurological disorders. In …