Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 44 for “"Systemic Inflammatory Response"”.
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The systemic inflammatory response to dental plaque
… Bacteremia involving oral bacteria and the systemic inflammatory responses are mechanisms that could causally link oral and systemic diseases. Objective: To use an experimental gingivitis model (EGM) in 2 clinical studies to 1) examine the systemic inflammatory responses to dental plaque, …
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Matrix metalloproteinases in the equine systemic inflammatory response: implications for equine laminitis
Laminitis is a crippling and often life-threatening disease of the equine foot. Soft tissue damage characteristic of this disease has been associated with increased MMP activity. Therefore, it seems likely that MMPIs could be potential therapeutic agents for laminitis. Further characterization of …
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Glucocorticoid Receptor Density and Binding Affinity in Horses with Systemic Inflammatory Response Syndrome
… the HPA axis in adult horses presenting with systemic inflammatory response syndrome (SIRS), and to determine where any alterations in HPA axis function occur in these patients compared to healthy adults. For the first part of the study, peripheral venous blood was collected from 3 healthy …
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Role of the systemic inflammatory response in the clinical and biological features of incurable cancer and cachexia
… of cancer is widely accepted. The same inflammatory processes are also involved in the evolution of the clinical features of cancer. Cachexia, a syndrome of muscle and fat loss not easily reversed by changes in nutrition, is amongst the most common and devastating features of cancer, …
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Serum calcitonin gene-related peptide concentrations in the horse and their relationship to the Systemic Inflammatory response
Systemic inflammation is a leading cause of mortality and morbidity in both human and equine intensive care patients. This systemic inflammatory response may be due to insult from bacterial, viral, fungal or parasitic invasion or from trauma or hypoxemia. Local and systemic release of a wide …
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An investigation of the systemic inflammatory response in the peri-operative period in patients undergoing potentially curative surgery for colorectal cancer
… specific survival but also the host immune response. Part of this host response is the non-specific systemic inflammatory response. There is now a body of work examining the relationship between the systemic inflammatory response and cancer specific survival. Indeed, there is evidence that …
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The role of the systemic inflammatory response, the JAK STAT pathway and the MAPK pathway in the prognosis of resectable pancreatic cancer
… at staging or surgery. A pre-operative systemic inflammatory response (as measured by CRP) is known to be associated with a poor prognosis in a number of cancers including pancreatic cancer. The reasons behind this poor prognosis are not yet known. The main driver of plasma CRP levels is …
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Chemokines as therapeutic targets in systematic inflammatory response syndrome
Exaggerated systemic inflammatory response syndrome may lead to multiple organ dysfunction, organ failure and eventually death. Chemokines, a large family of small chemotactic cytokines, are critical inflammatory mediators in the development of both acute pancreatitis and sepsis. The present study …
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Predicting hyperlactatemia in the ICU
Sepsis, which occurs when an infection leads to a systemic inflammatory response, is believed to contribute to one in two to three hospital deaths in the United States. Using the Multiparameter Intelligent Monitoring in Intensive Care (MIMIC II) database of electronic medical records from Boston's …
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Prognostické a prediktivní markery v léčbě karcinomu pankreatu
… Prognostic parameters based on the presence of systemic inflammation have a significant role in many cancers. Inflammation is known to promote tumor progression, leading to shortened survival. In pancreatic cancer, systemic inflammation is common and contributes to its unfavorable prognosis. The …
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Extracorporeal Circulation: Effect of Long-Term (24-Hour) Circulation on Blood Components
… harmful side effects such as stroke and/or systemic inflammatory response in patients. Reactions of blood components to extracorporeal circulation include complement and inflammatory reactions, coagulation and thrombogenesis, frank hemolysis, and platelet activation and adhesion to the …
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Metabolic engineering analysis of post-burn hepatic hypermetabolism
… as hypermetabolism that is associated with the systemic inflammatory response to severe injury. At the whole body level, hypermetabolism is characterized by elevated resting energy expenditure and increased turnover of proteins, fatty acids, and carbohydrates.
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A retrospective audit of the clinical value of routine chest radiographs in the first 24 hours after cardiac surgery using medical records
… pulmonary dysfunction (PPD), where systemic inflammatory response due to cardiopulmonary bypass is the main culprit [Milot J et al, 2001] - leading to acute lung injury. Over and above the usual cardiovascular diseases that require surgical intervention, in Sub-Saharan Africa, …
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Improving Early Sepsis Identification on Inpatient Units
… of severe infection characterized by a systemic inflammatory response (SIRS). As a time critical illness requiring early identification and treatment, delayed recognition of sepsis can lead to organ failure and death. Effective sepsis protocols need to be established and implemented to …
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Host response in sepsis
Sepsis is a serious condition characterized by a systemic inflammatory response to an infection. Increased vascular leakage, vasodilation and heart failure cause circulatory disturbances challenging the intensivist. Despite modern medication and high technology supportive care, mortality is high. …
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An investigation of liver blood flow in systemic inflammation
Inflammatory stimuli such as infection or tissue injury will produce a local inflammatory response which may, if the inflammatory response is sufficiently large, spill over to produce a systemic inflammatory response. This is clinically characterized by a response in heart and respiratory rate, a …
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The impacts of psychological stress on innate-like invariant T cell survival, phenotype, and function
… critical roles in the regulation of immune responses. Consequently, psychological stress can result in immunosuppressive states that are conducive to the development of infection and cancer. Yet, whether stress impacts the functions of innate-like T lymphocytes including invariant natural …
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Uždegimo žymenų reikšmė ankstyvam ūminio pankreatito eigos prognozavimui: perspektyvinio daugiacentrio kohortinio tyrimo rezultatai /
… as well as in peripancreatic fat and involved in inflammatory response. Increase of fatty tissue due to obesity is associated with the amplified systemic inflammatory response in AP. It is hypothesized that peripancreatic necrosis can cause the massive release of adipokines into the patient’s …
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The value of inflammation markers in early acute pancreatitis course prediction: the results of prospective multicenter cohort study /
… as well as in peripancreatic fat and involved in inflammatory response. Increase of fatty tissue due to obesity is associated with the amplified systemic inflammatory response in AP. It is hypothesized that peripancreatic necrosis can cause the massive release of adipokines into the patient’s …
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Early Identification of Sepsis in the Walk-in Setting
Sepsis is the body’s dysregulated response to infection and is the cause of significant physical and financial burden on patients and the healthcare system. If not identified and treated promptly, sepsis can result in high rates of morbidity and mortality. Prehospital settings, such as walk-in …
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