Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Systembiologie"”.
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Entwicklung und Evaluation von fächerübergreifenden Bildungsangeboten im Schüler*innenlabor teutolab-biotechnologie
… miteinander verbinden.<br /> Die Projektwoche Systembiologie: biologisch experimentieren – mathematisch modellieren wurde von 105 interessierten Oberstufenschüler\*innen durchgeführt. An dem Kurs Enzymkinetik von Lactase – Lactoseintoleranz verstehen und berechnen nahmen 203 Schüler\*innen aus …
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Computational models for the study of responses to infections
… infektiöse Krankheiten mit globalen Methoden („Systembiologie“) bioinformatisch zu untersuchen. Im ersten Teil wird der Apoptose-Signalweg analysiert. Apoptose (Programmierter Zelltod) wird bei verschiedenen Infektionen, zum Beispiel bei Viruserkrankungen, als Abwehrmaßnahme eingesetzt. Die …
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Analysing concerted criteria for local dynamic properties of metabolic systems
Metabolic systems tend to exhibit steady states that can be measured in terms of their concentrations and fluxes. These measurements can be regarded as a phenotypic representation of all the complex interactions and regulatory mechanisms taking place in the underlying metabolic network. Such …
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Comparative analysis of molecular interaction networks : the interplay between spatial and functional organizing principles
The study of biological interaction networks is a central theme in systems biology. Here, we investigate common as well as differentiating principles of molecular interaction networks associated with different levels of molecular organization. They include metabolic pathway maps, protein-protein …
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A model for sigma factor competition in bacterial cells
Bacteria respond to changing environmental conditions by switching the global pattern of expressed genes. In response to specific environmental stresses the cell activates several stress-specific molecules such as sigma factors. They reversibly bind the RNA polymerase to form the so-called …
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Reasoning on the response of logical signaling networks with answer set programming
Deciphering the functioning of biological networks is one of the central tasks in systems biology. In particular, signal transduction networks are crucial for the understanding of the cellular response to external and internal perturbations. Importantly, in order to cope with the complexity of …
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Evolutionary fingerprints in genome-scale networks
Mathematical modeling of biological phenomena has experienced increasing interest since new high-throughput technologies give access to growing amounts of molecular data. These modeling approaches are especially able to test hypotheses which are not yet experimentally accessible or guide an …
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A systems biological approach towards the molecular basis of heterosis in Arabidopsis thaliana
Heterosis is defined as the superiority in performance of heterozygous genotypes compared to their corresponding genetically different homozygous parents. This phenomenon is already known since the beginning of the last century and it has been widely used in plant breeding, but the underlying …
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The plant cytoskeleton as a transportation network
The cytoskeleton is an essential component of living cells. It is composed of different types of protein filaments that form complex, dynamically rearranging, and interconnected networks. The cytoskeleton serves a multitude of cellular functions which further depend on the cell context. In animal …