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Showing 1 to 1 of 1 for “"Synthetic viability"”.

  1. Focused CRISPR-Cas9 screens investigating the DNA damage response

    The DNA damage response (DDR) consists of a complex network of interconnected pathways which detect and repair damaged DNA, maintaining genome integrity. Somatic mutations in DDR genes are associated with tumour development, while germline mutations cause a spectrum of disorders ranging from …

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