Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Synthetic gene circuit"”.
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Self-organized Pattern Formation using Engineered Bacteria
… gradients, which are either predefined or generated as part of the patterning processes. However, using E. coli programmed by a simple synthetic gene circuit, I demonstrate here the generation of robust, self-organized ring patterns of gene expression in the absence of an apparent morphogen …
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Degenerate oligonucleotide primed amplification of genomic DNA for combinatorial screening libraries and strain enrichment
… vector, this is referred to as a DNA library. Generating quality DNA libraries that incorporate broad genetic diversity is challenging, despite the availability of published protocols. In response, a novel, efficient, and reproducible technique for creating DNA libraries was created in this …
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Towards dissecting neural ensembles : development of genetic profiling and targeting approaches
The recent development of genetic neural modulation technologies has brought about a renaissance in systems neurobiology, where manipulation of specific neural ensembles coupled with measurements of the resulting behavioral changes have begun to chart the functional organization of the brain. …
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Bistability, Synthetic Biology, and Antibiotic Treatment
… focused primarily on cellular mechanisms that generate bistable switches and their impact on cellular dynamics. </p><p>Here, I study emergent bistability due to bacterial interactions with either synthetic gene circuits or antibiotics. A synthetic gene circuit is often engineered by considering …
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Functional Analysis of Synthetic Gene Circuits Controlling A Protein Pump In Yeast
<p>Synthetic biology aims to build biological devices to understand living systems and explore new applications. Synthetic gene circuits such as genetic switches, oscillators and logic gates are at the core of many synthetic biology applications. These gene circuits often include a sensor/regulator …
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Development of a reliable screening platform for PET hydrolysing enzymes in an ultra-high throughput setup
… Since PHEs stem from different enzyme families general findings on one PHE cannot easily be transferred to other known PHEs. Thus functional assays that are compatible with high throughput screens would enable far larger explorations of protein sequence space and thus increase the probability to …