Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Synthetic Community"”.
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New Strategies in Radical Chemistry and Their Application to the Construction of C(sp3)–C(sp3) Bonds in the Giese Reaction
… remains of significant interest for the synthetic community. In this thesis, a unique platform to access C(sp³)-centred radicals, and their subsequent addition into electron deficient olefins to build saturated hydrocarbon frameworks (the Giese reaction), is investigated. The …
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Beneficial Fungal Secretome and Synthetic Consortia to Improve Soybean Growth During Drought Stress
… goal was to build a naturally occurring fungal synthetic community (FunSynCom) to improve growth and drought resilience in soybeans. In this study, we isolated, identified, and characterized a set of fungal endophytes from the rhizosphere of halophytic plants during a low-tide summer with …
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Synthetic Efforts Toward Hypoestoxide, Platensimycin, And Guttiferone G
… makes it a target of great interest to the synthetic community. The synthesis of this molecule's complex macrocyclic core was accomplished by using relay ring closing metathesis, and post-cyclization modifications were controlled by the shape of the molecule. Platensimycin is a recently …
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A novel photocatalytic strategy for complex aliphatic amine synthesis and the total synthesis of alkaloids (−) FR901483 and (+)-TAN1251C
… amines and enamines, enabling the generation of synthetically valuable $\alpha$-tertiary amines. $\alpha$-Tertiary amines are a common feature in a number of bioactive natural products. Immunosuppressant ($-$)-FR901483 (1) and muscarinic antagonist ($+$)-TAN1251C (2) are biosynthetically related …
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Synthetic Studies of the Rubellin Natural Products
… dimers within the past 20 years. The scientific community has found deep interest in the anthraquinone class of compounds due to their therapeutic properties and challenging structural elements. Various architecturally beautiful natural products have been successfully synthesized utilizing two …
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Total synthesis of polycyclic natural products : synthetic studies on (+)-ineleganolide, (–)-sinulochmodin C, verrillin hydrate, and aleutianamine.
… that have captured and held the attention of the synthetic and biomedical communities for nearly three decades. Their daunting polycyclic molecular architectures, coupled with promising biological activities and intriguing biosynthetic relationships have rendered these natural products as …
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Strategies and Tactics for the Synthesis of Polycyclic Alkaloids
… alkaloids has attracted the attention of the synthetic community, with several syntheses of the monomeric myrmicarins completed. Significant effort has been put forth toward the synthesis of the higher order structures, though no successful approach has been reported to date. These isolation …
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Chemical Investigations in Complex Alkaloid Synthesis
… Complex alkaloids have been of interest to synthetic chemists for decades where their intriguing chemical structures have led to the development of new reactions as well as provided biologically relevant compounds for potential therapeutic use. The growing Myrioneuron and Sarpagine- related …
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Microbial profiling using metagenomic assembly
… was demonstrated to faithfully reconstruct a synthetic community in terms of richness and abundance. To facilitate the use of mPUMA, a software package was developed and released under an open source license. The utility of mPUMA was further examined through the characterization of the …
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Total synthesis of marine terpenoids
… scaffolds have served as a proving ground for synthetic chemists, inspiring them to develop, assess, and test new methodologies and disconnections. Moreover, besides advancing the field of organic synthesis, marine natural products have also had an immense influence on medicinal chemistry …