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Showing 1 to 5 of 5 for “"Synthesis Of Pharmaceuticals"”.
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Isolation, identification and characterisation of novel actinobacteria from Zambian hot-springs
… which has been extensively exploited, members of other genera including Micromonospora have been shown to be a promising source of novel secondary metabolites and enzymes.The biocatalytic conversion of 5-monosubstituted hydantoin derivatives to optically pure amino acids involves two reaction …
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ADVANCING MULTIPHASE PROCESS DEVELOPMENT WITH HYBRID PHYSICS-BASED – MACHINE LEARNING MODELS
… are widely used in the chemical industry for the synthesis of pharmaceuticals, fine chemicals, and bulk intermediates. However, scaling up such systems is challenging due to the coupled effects of mass transfer and intrinsic reaction kinetics, both of which can control overall process behaviour. …
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Characterisation of the structural stability of transketolase under biocatalytically relevant conditions
… regulation. TK catalyses the interconversion of sugars by transferring a two-carbon ketol unit from a ketose donor substrate to an aldolase acceptor substrate. It is also an important biocatalyst in stereo-specific carbon-carbon bond synthesis with potential industrial application for the …
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Part I. Rhodium-catalyzed asymmetric functionalization of allylic amines Part II. Harnessing kinetic driving forces in alkyne metathesis for the synthesis of complex molecular architectures
Part I of this Dissertation describes the rhodium catalyzed asymmetric functionalization of allylic amines to form chiral products such as β-branched amides and esters, and γ-branched amines. We developed a modular synthetic strategy that enables the diversification of a single allylic amine …
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Expanding the scope of allylic C—H aminations via electrophilic palladium(II) catalysis
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-08-01