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Showing 1 to 20 of 69 for “"Synovial Fluid"”.
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Investigating Synovial Fluid Electrochemical Properties Against Orthopaedic Alloys
… corrosion processes that occur at the CoCrMo-synovial fluid interface. The first study investigates the electrochemical behavior of CoCrMo in human synovial fluid obtained at the time of primary TKA, using CoCrMo in phosphate-buffered saline (PBS) as a comparison. The second study compares the …
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Hyporesponsive synovial fluid T cells in rheumatoid Arthritis
… role in pathogenesis. Both chronically inflamed synovial tissue and synovial fluid (SF) are usually rich in infiltrated CD4+ T helper cells (TH cells) and CD8+ cytotoxic T cells (CTL). Only T cells isolated from the SF of many RA patients were anergic upon their activation in vitro by stimulation …
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Mechanisms of synovial fluid lipid-mediated neuronal sensitisation in arthritis
… targets is to use human samples, such as synovial fluid (SF), in pre-clinical research. SF lubricates healthy synovial joints, like the knee, and has been shown to have elevated levels of various inflammatory mediators, such as peptide nerve growth factor (NGF), which correlates with pain …
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The Effects of Synovial Fluid and Inflammatory Cells on Orthopaedic Implant Alloys
… and inflammation can alter the composition of Synovial Fluid (SF), potentially causing implant corrosion and the release of metal ions into the surrounding tissue. These metal ions can trigger innate and adaptive responses, further enhancing implant corrosion. As the number of primary TKA …
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Effect of a single intra-articular injection of bupivacaine on synovial fluid prostaglandin E2 concentrations in normal canine stifles
… The aim of this study was to compare synovial fluid PGE2 concentrations after a single intra-articular injection of bupivacaine with a saline control in normal canine stifles. We hypothesized that bupivacaine stifles would have a significantly elevated PGE2 concentration compared to …
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A Study of the Intra-Articular Temperature, the Synovial Fluid Viscosity,and the Cellular Components in Joint Disease of the Horse
Made available in DSpace on 2014-12-09T22:30:23Z (GMT). No. of bitstreams: 1 6915371.pdf: 2922014 bytes, checksum: 62b6a6012061a99dc870716d47293e93 (MD5) Previous issue date: 1969
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The Influence of Maximal and Submaximal Cyclic Concentric and Eccentric Exercise on Chondrocyte Death and Synovial Fluid Proteins in the Rabbit knee
… known about the effects of exercise loading on synovial fluid (SF) composition and chondrocytes viability. The purpose of this study was to load intact knee joints with two types of controlled maximal muscular contractions (low, and high intensity exercise) and identify changes in synovial fluid …
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Equine Septic Arthritis and Serum Amyloid A
… diagnosed primarily based on clinical signs and synovial fluid cytology. Septic synovial fluid is characterized by significant elevations in total protein (TP) and total nucleated cell count (TNCC). However, in some cases it can be difficult to distinguish between septic arthritis and non-septic …
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Research on the Participation of Humoral Factors of Congenital Immunity in the Pathogenesis of Activated Osteoarthritis // Изследване участието на хуморалните фактори на вродения имунитет в патогенезата на активираната остеоартроза
… fractions are examined in blood plasma and synovial fluid. Statistical analysis of the collected data shows that the average percentage of CRP levels in synovial fluid is 42.14% of plasma levels, higher than the normal 20%. The average percentages of C3 and C4 levels in synovial fluid are …
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Novel approaches to evaluate osteoarthritis in the rabbit lateral meniscectomy model
… compared to the surgical control. Secondly, synovial fluid was harvested from the 12 rabbits on days 0, 6, 26, 40, and 57 with surgery occurring on day 12. Trypan blue was used in the lavage fluid to estimate the volume of harvested synovial fluid. There was a significant increase in the …
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Hempseed oil as a novel source of polyunsaturated fatty acids and its effect on inflammation in sedentary horses
… uniform feeding rate from d 36 to 63. Serum and synovial fluid PUFA reflected dietary intake. GLA was greater in serum (0.465 vs. 0.046; P < 0.0001) and synovial fluid (0.270 vs. 0; P < 0.0001) in horses fed HSO compared to CON. This contributed to greater dihomo-γ-linolenic acid (DGLA) …
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Biotribology: articular cartilage friction, wear, and lubrication
… saline solution, bovine serum, and bovine synovial fluid. Synovial fluid as a lubricant produced the least amount of damage to the cartilage. Serum produced more wear and damage than synovial fluid, but less than buffered saline (which produced the most damage). Three-hour tests produced …
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Biotribology: The Effect of Lubricant and Load on Articular Cartilage Wear and Friction
… reference + hyaluronic acid, and bovine synovial fluid) were tested and evaluated using several analysis techniques. These techniques included wear analysis by hydroxyproline measurement, scanning electron microscopy (SEM), histologic sectioning and staining, numerical analysis of …
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Macrophage-mediated regulation of joint homeostasis
… correlated with gross pathology, histology, and synovial fluid cytokines. M1 and M2 markers were co-expressed in normal and osteoarthritic joints, varying in intensity of expression according to degree of inflammation. Concentrations of synovial fluid IL-10, a macrophage-produced cytokine that is …
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Biotribology: Studies of the Effects of Biochemical Environments on the Wear and Damage of Articular Cartilage
… and lubrication of biological systems, mainly synovial joints such as the human hip and knee. Osteoarthritis (OA) is partially characterized by the loss of articular cartilage from the contacting surface of the articulating bones in synovial joints. Although it has been studied extensively, the …
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Bone Marrow Mononuclear Cell for Equine Joint Disease
… and objectively evaluated for lameness and synovial fluid collected (cytology and cytokine/growth factor quantification) at 0, 7, and 21 days post-injection. Data were analyzed using General Estimating Equations with significance set at P<0.05. There were no adverse effects noted in any …
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Charge-based transport and drug delivery into cartilage for localized treatment of degenerative joint diseases
Traumatic joint injuries significantly increase synovial fluid levels of pro-inflammatory cytokines that can initiate cartilage degeneration leading to osteoarthritis (OA). Articular cartilage is a highly negatively charged, avascular tissue, which relies on synovial fluid convection and …
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(1) Artificial Synovial Fluid and Cartilage. (2) Non-Manumitative GD3+ Hosts as MRI Contrast Agents. (3) Five-Member Heterocycles as Switchable Ferromagnetic Coupling Units. (4) Liquid Crystal Opto-Optical Switch: Non-Destructive Information Retrieval Based on a Photochromic Fulgide as Trigger
Chapter III describes a series of 1,3-, 2,5-, and 2,4-dimethylene five-member heterocycles as new ferromagnetic coupling units. Full geometry optimization of structures with heteroatoms ranging from Be to O and from Mg to S at the CASSCF level with energy calculation at the MCQPDT2 level allowed …
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Mechanisms of Impaired Efferocytosis of Synovial Macrophages in Knee Osteoarthritis
… primary blood monocytes, which were treated with synovial fluid from patients with high levels of inflammation due to knee OA. By feeding labeled apoptotic cells to macrophages stimulated with synovial fluid and fixing the cells during the process of efferocytosis, we were able to identify the …
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